Results 41 to 50 of about 185,231 (352)

Controlled Delivery of Sdf-1 Alpha and Igf-1: Cxcr4(+) Cell Recruitment and Functional Skeletal Muscle Recovery [PDF]

, 2015
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Farrar, Roger P., Hammers, David W., Hsieh, Pei-Ling, Merscham-Banda, Melissa, Pham, Chantal B., Rybalko, Viktoriya Y., Suggs, Laura J.   +6 more
core   +1 more source

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P., Leuvenink, Henri G. D., Nieuwenhuijs-Moeke, Gertrude J., Pischke, Soren E., Ploeg, Rutger J., Pol, Robert A., Sanders, Jan Stephan F., Struys, Michel   +7 more
core   +2 more sources

In-hospital prognosis and long-term mortality of STEMI in a reperfusion network. “Head to head” analisys: invasive reperfusion vs optimal medical therapy

BMC Cardiovascular Disorders, 2017
Background ST Segment Elevation Acute myocardial infarction (STEMI) preferred treatment is culprit artery reperfusion with primary percutaneous coronary intervention (PPCI). We ought to analyze the benefit of early reperfusion vs. optimal medical therapy
C . García-García, N. Ribas, L. L. Recasens, O. Meroño, I. Subirana, A. Fernández, A. Pérez, F. Miranda, H. Tizón-Marcos, J. Martí-Almor, J. Bruguera, R. Elosua   +11 more
doaj   +1 more source

Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]

, 2016
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core   +2 more sources

Reperfusion and cytoprotective agents are a mutually beneficial pair in ischaemic stroke therapy: an overview of pathophysiology, pharmacological targets and candidate drugs focusing on excitotoxicity and free radical

Stroke and Vascular Neurology
Stroke is the second-leading cause of death and the leading cause of disability in much of the world. In particular, China faces the greatest challenge from stroke, since the population is aged quickly.
Mingyu Chen, Dongya Zhu, Xiumei Xu
doaj   +1 more source

Acute Ischaemic Stroke in Infective Endocarditis: Pathophysiology and Clinical Outcomes in Patients Treated with Reperfusion Therapy

Immuno, 2021
Infective endocarditis in the setting of acute stroke poses a clinical challenge given the high mortality and morbidity associated with the condition. The pathophysiological mechanisms including clinical and imaging biomarkers that can provide insights ...
Rohan Maheshwari, Daniel Wardman, Dennis John Cordato, Sonu Menachem Maimonides Bhaskar   +3 more
doaj   +1 more source

Reperfusion therapy of acute myocardial infarction [PDF]

Progress in Cardiovascular Diseases, 1988
I N 1979, DUCKERT reviewed the completed trials of intravenous (IV) thrombolytic therapy in acute myocardial infarction (MI) for this journal.’ Duckert stated in his review, “It is fair to conclude that today the value of thrombolytic treatment of acute MI has not been established.” Since this review, dramatic advances have been made in the ...
O'Neill, William W., Topol, Eric J., Pitt, Bertram   +2 more
openaire   +3 more sources

Specific features of reperfusion therapy for vertebrobasilar ischemic stroke

Неврология, нейропсихиатрия, психосоматика, 2015
Ischemic stroke in the vertebrobasilar system (VBS) is characterized by the high rates of death and disability; reperfusion therapy in patients with a lesion focus in the VBS is safe and effective beyond the 4.5-hour therapeutic window.
K. V. Anisimov, A. P. Tolmachev, Nikolai Anatolyevich Shamalov   +2 more
doaj   +1 more source

Imaging Acute Stroke: From One-Size-Fit-All to Biomarkers

Frontiers in Neurology, 2021
In acute stroke management, time window has been rigidly used as a guide for decades and the reperfusion treatment is only available in the first few limited hours.
Jianfei Lu, Qiyong Mei, Xianhua Hou, Anatol Manaenko, Lili Zhou, David S. Liebeskind, John H. Zhang, Yao Li, Qin Hu   +8 more
doaj   +1 more source

Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]

, 2002
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Aicher, A, Assmus, B, Britten, M, Dimmeler, S, Döbert, N, Grünwald, F, Hoelzer, D, Lehmann, R, Martin, H, Schächinger, V, Teupe, C, Urbich, C, Zeiher, AM   +12 more
core   +1 more source