Results 91 to 100 of about 889,250 (400)

Overview of methodologies for T-cell receptor repertoire analysis

open access: yesBMC Biotechnology, 2017
BackgroundThe T-cell receptor (TCR), located on the surface of T cells, is responsible for the recognition of the antigen-major histocompatibility complex, leading to the initiation of an inflammatory response.
E. Rosati   +5 more
semanticscholar   +1 more source

Sound production in the Meagre, Argyrosomus regius (Asso, 1801): intraspecific variability associated with size, sex and context [PDF]

open access: yes, 2020
Many fish taxa produce sound in voluntary and in disturbance contexts but information on the full acoustic repertoire is lacking for most species. Yet, this knowledge is critical to enable monitoring fish populations in nature through acoustic monitoring.
Amorim, Maria Clara P.   +6 more
core   +3 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The Repertoires of Slovak and Slovenian Theatre Houses and their Productions of the Western European and American Authors (1945 – 1970)

open access: yesSlovenské divadlo, 2017
This article is a comparative review of performances of Western European and American authors in Slovak and Slovenian theatres in the two decades after World War II.
Andres Rok
doaj   +1 more source

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

open access: yesNature Communications, 2017
γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use next-generation sequencing to probe how this paradigm relates to human Vδ2neg T cells, implicated in ...
M. Davey   +11 more
semanticscholar   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Intelligent recommendation algorithm for piano tracks based on the CNN model

open access: yesNonlinear Engineering
In order to improve the effect of intelligent recommendation of piano repertoire, this article combines the convolutional neural network (CNN) model to perform intelligent analysis of piano repertoire and combines personal preference for piano repertoire
Zhang Qi
doaj   +1 more source

SCF E3 Ligase Substrates Switch from CAN-D to Can-ubiquitylate

open access: yes, 2018
Liu et al. (2018) report a mathematical model predicting how the cellular repertoire of SCF E3 ligases is assembled by “adaptive exchange on demand,” with the limited pool of CUL1 scanning the vast sea of F-box proteins for those with substrates ...
Schulman, B., Scott, D.
core   +1 more source

A comparative study of the function of heterospecific vocal mimicry in European passerines [PDF]

open access: yes, 2007
Although heterospecific vocal imitation is well documented in passerines, the evolutionary correlates of this phenomenon are poorly known. Here, we studied interspecific variation in vocal mimicry in a comparative study of 241 European songbirds.
Anders Pape Møller   +72 more
core   +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun   +95 more
wiley   +1 more source

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