Results 271 to 280 of about 889,250 (400)

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Transcriptomic Insights Into the Immune Repertoire of an Antarctic Sponge. [PDF]

Ecol Evol
Daille LK, Moreno-Pino M, Hajdu E, Trefault N.   +3 more
europepmc   +1 more source

The positional repertoires of hominins: New insights from extant primates

, 2018
François Druelle, Mélanie Berthet, Benoît Quintard, Jesse W. Young, Peter Aerts, Gilles Bérillon   +5 more
openalex   +1 more source

Probability model for molecular recognition in biological receptor repertoires: significance to the olfactory system.

, 1993
Doron Lancet, Elena Sadovsky, Eyal Seidemann   +2 more
openalex   +2 more sources

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Peripheral Blood TCR Clonotype Diversity as a Biomarker for Colorectal Cancer. [PDF]

Bioengineering (Basel)
Zhu G, Chen T, Ma C, Liu K, Huang B, Yang G.   +5 more
europepmc   +1 more source

The challenges of modelling antibody repertoire dynamics in HIV infection

, 2015
Shishi Luo, Alan S. Perelson
openalex   +2 more sources

Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire.

Cancer Research, 2017
D. Oh, J. Cham, Li Zhang, Grant Fong, S. Kwek, M. Klinger, M. Faham, L. Fong   +7 more
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase. [PDF]

Nucleic Acids Res
Lees WD, Peres A, Klein V, Amos N, Jana U, Engelbrecht E, Vanwinkle Z, Malach Y, Konstantinovsky T, Polak P, Watson CT, Yaari G.   +11 more
europepmc   +1 more source