Results 311 to 320 of about 889,250 (400)

B cell receptor repertoire reconstitution in patients with neuromyelitis optica spectrum disorder receiving B-cell depletion therapy. [PDF]

Front Immunol
Kim HJ, Shin W, Seo D, Jang I, Ryu J, Choi L, Kim J, Kim H, Lim YM, Lee EJ.   +9 more
europepmc   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

A Three Factor Model of Parental Coping With Childhood Cancer. [PDF]

Psychooncology
Hamtzani O, Dolgin MJ, Kushnir T.
europepmc   +1 more source

The role of Research‐Practice Ambassadors in strengthening socially just and equitable partnership processes

American Journal of Community Psychology, EarlyView.
Abstract Research‐Practice Partnerships seek to close the research‐practice gap through developing collaborative, authentic partnerships between researchers and community members. Our team has leveraged Research‐Practice Ambassadors to support socially just and equitable partnership processes in schools.
Danielle R. Hatchimonji, Lauren McNeela, Zumana Noor, Melissa Stoffers, Tia N. Barnes, Kira Branch, Danika Perry, Amanda Parks, Mariam Berthe   +8 more
wiley   +1 more source

A High-Throughput Sequencing Strategy for Clinical Repertoire Profiling of T Cell Receptor Beta Chain: Development and Reference Values Across Healthy Adults, Paediatrics, and Cord Blood Units. [PDF]

Int J Mol Sci
Enrich E, Antón-Iborra M, Hobeich C, Mora-Buch R, Lara-de-León AG, Parra-Martínez A, Sánchez B, Vidal F, Soler-Palacin P, Rudilla F.   +9 more
europepmc   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

B-Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization. [PDF]

Allergy
Gill KK, Moore C, Nwogu O, Kroner JW, Chang WC, Burkle J, Virolainen SJ, Stevens ML, Baatyrbek A, Miraldi ER, Biagini JM, Devonshire AL, Kottyan L, Schwartz JT, Assa'ad AH, Martin LJ, Andorf S, Khurana Hershey GK, Roskin KM.   +18 more
europepmc   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

Annals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen, Jaden Thomas, Xianhui Chen, Jaden Zelidon, Mariam Najeeb, Abigayle Hahn, Ping Zhang, Aaron Sathyanesan, Bin Gu   +8 more
wiley   +1 more source

Dynamics of B-cell response in MERS-CoV patients and survivors with hybrid immunity. [PDF]

mBio
Al-Khatib HA, Ali FH, Zedan HT, Smatti MK, Coyle PV, Taleb SA, Hssain AA, Al-Thani AA, Yassine HM.   +8 more
europepmc   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

Annals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf, Maria Eveslage, Timo Wirth, Christian Wünsch, Eva M. Schumann, Jan D. Lünemann, Heinz Wiendl, Luisa Klotz, Nicholas Schwab   +8 more
wiley   +1 more source