Results 321 to 330 of about 889,250 (400)

Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection. [PDF]

Front Immunol
Zeng L, Liu L, Ren B, Feng B, Lai X, Lai X, Chen Z, Huang Y, Hong W.   +8 more
europepmc   +1 more source

An Expanded Toolbox for Versatile Chemical Editing of Adeno‐Associated Virus

Angewandte Chemie, EarlyView.
We describe technology to introduce diverse non‐natural chemical functionalities site‐specifically into the capsid of adeno‐associated virus through genetic code expansion, and using them to engineer this leading vector for human gene therapy for enhanced tissue specificity and reduced immunogenicity Abstract Site‐specific incorporation of noncanonical
Quan Pham, Jake Glicksman, Boyang Han, David Koo, Conor Loynd, Soumya Jyoti Singha Roy, Abhishek Chatterjee   +6 more
wiley   +1 more source

HLA and T-Cell Receptor Investigations in Idiopathic and Paraneoplastic Opsoclonus-Myoclonus in Children. [PDF]

Neurol Neuroimmunol Neuroinflamm
Olivé-Cirera G, Muñoz-Sánchez G, Palou E, Ruiz García R, Fonseca EG, Luchoro JF, Aguilera-Albesa S, Maudes E, Martinez-Hernandez E, Sabater L, Dalmau JO, González A, Armangue T.   +12 more
europepmc   +1 more source

Dynamischer Austausch von Bindemolekülen steigert die Effizienz der Proteinmarkierung in DNA‐PAINT um das bis zu 15‐Fache

Angewandte Chemie, EarlyView.
Der dynamische Austausch von Bindemolekülen (Dynamic Binder Exchange; DyBE) nutzt transiente Binde–Zielprotein‐Interaktionen, um die Markierungseffizienz in der superauflösenden Mikroskopie um das 15‐Fache zu steigern. DyBE kartiert die Organisation von Rezeptor‐Tyrosinkinasen (RTKs), einschließlich HER2‐Homodimere und EGFR–HER2‐Heterodimere, auf der ...
Clemens Steinek, Isabelle Pachmayr, Sebastian Strauss, Monique Honsa, Jisoo Kwon, Ralf Jungmann   +5 more
wiley   +1 more source

Antibodies and cryptographic hash functions: quantifying the specificity paradox. [PDF]

Front Immunol
Petrella RJ.
europepmc   +1 more source

Growth, Dissolution and Segregation of Genetically Encoded RNA Droplets by Ribozyme Catalysis

Angewandte Chemie, EarlyView.
Ribozymes enable sequence‐encoded turnover of RNA droplet material, resulting in transiently active droplets that selectively segregate based on their genotype. This establishes a direct link between genetic information and droplet behavior, marking a step toward programmable, evolvable RNA‐based compartments with life‐like properties.
Franziska Giessler, William Verstraeten, Tobias Abele, Stefan J. Maurer, Luca Monari, Kerstin Göpfrich   +5 more
wiley   +1 more source

Machine learning reveals distinct T-cell receptor clusters in plasma cell dyscrasias compared to healthy controls. [PDF]

PLoS One
Coffey DG, Zhang Y, Hill E, Cross F, Philip R, Theoret MR, Landgren O, Baines AC, Kazandjian D.   +8 more
europepmc   +1 more source

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn's disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn's disease. [PDF]

Front Immunol
Mahdy AKH, Schöpfel V, Huppertz-Hauss G, Perminow G, Tran F, Bang C, Hov JR, Bengtson MB, Ricanek P, Opheim R, Aabrekk TB, Detlie TE, Kristensen VA, Poyet M, Høivik ML, Franke A, ElAbd H.   +16 more
europepmc   +1 more source

Symptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells. [PDF]

mBio
Johansson E, Lee Y, Fajardo-Rosas V, Abawi A, Logandha Ramamoorthy Premlal A, Frazier A, Greenbaum JA, Vijayanand P, da Silva Antunes R, Sette A.   +9 more
europepmc   +1 more source

Exploration of the benefits and resistance mechanisms of immunotherapy based on PD-L1 expression, circulating tumor DNA and T-cell receptor profiles in advanced gastric cancer. [PDF]

Cancer Immunol Immunother
Gou M, Qian N, Zhang Y, Yan B, Wang Z, Dai G.   +5 more
europepmc   +1 more source