Results 51 to 60 of about 313,114 (266)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Validation of the ACGIH TLV for hand activity level in the OCTOPUS cohort: a two-year longitudinal study of carpal tunnel syndrome

open access: yesScandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: This study aimed to evaluate the risk of musculoskeletal disorders to the hand-wrist system. The American Conference of Governmental Industrial Hygienists (ACGIH) proposed threshold limit values (TLV©) based on hand activity level (HAL) and ...
Roberta Bonfiglioli   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

La iconicidad de la reduplicación léxica en español [PDF]

open access: yesEstudios Interlingüísticos, 2019
El objetivo del presente estudio consiste en examinar la motivación icónica de la reduplicación léxica en español. Como la reduplicación en distintas lenguas está asociada al fenómeno de la iconicidad, el presente artículo pretende averiguar si un tipo ...
Ewa Urbaniak
doaj  

THE TEXTUAL ROLE OF REPETITION IN THE TRANSLATION OF POLISH AND HUNGARIAN LEGAL TEXTS

open access: yesComparative Legilinguistics, 2009
This article presents research on written legal texts with a focus on the cohesion of such texts by analyzing the function of lexical repetition. The author indicates the possibility of using Hoey and Károly’s method of researching repetition patterns in
Karolina KACZMAREK
doaj   +1 more source

The Undirected Repetition Threshold [PDF]

open access: yes, 2019
For rational ...
James D. Currie, Lucas Mol
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Car le temps est proche : la crise écologique et l’apocalypse sans cesse annoncée

open access: yesSocio-anthropologie, 2013
The expression “there is still a solution but time is running out” is often found in the reports on the ecological crisis. It is a rhetorical statement which is not scientific, but whose inclusion seems almost mandatory for political reasons.
Ernest Garcia
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy