Results 51 to 60 of about 300,274 (266)

Non-Repetitive Tilings [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2002
In 1906 Axel Thue showed how to construct an infinite non-repetitive (or square-free) word on an alphabet of size 3. Since then this result has been rediscovered many times and extended in many ways. We present a two-dimensional version of this result.
Currie, James D., Simpson, Jamie
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Undirected Repetition Threshold [PDF]

open access: yes, 2019
For rational ...
James D. Currie, Lucas Mol
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Validation of the ACGIH TLV for hand activity level in the OCTOPUS cohort: a two-year longitudinal study of carpal tunnel syndrome

open access: yesScandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: This study aimed to evaluate the risk of musculoskeletal disorders to the hand-wrist system. The American Conference of Governmental Industrial Hygienists (ACGIH) proposed threshold limit values (TLV©) based on hand activity level (HAL) and ...
Roberta Bonfiglioli   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

La iconicidad de la reduplicación léxica en español [PDF]

open access: yesEstudios Interlingüísticos, 2019
El objetivo del presente estudio consiste en examinar la motivación icónica de la reduplicación léxica en español. Como la reduplicación en distintas lenguas está asociada al fenómeno de la iconicidad, el presente artículo pretende averiguar si un tipo ...
Ewa Urbaniak
doaj  

THE TEXTUAL ROLE OF REPETITION IN THE TRANSLATION OF POLISH AND HUNGARIAN LEGAL TEXTS

open access: yesComparative Legilinguistics, 2009
This article presents research on written legal texts with a focus on the cohesion of such texts by analyzing the function of lexical repetition. The author indicates the possibility of using Hoey and Károly’s method of researching repetition patterns in
Karolina KACZMAREK
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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