Results 71 to 80 of about 301,036 (267)
DIDACTIC PERSPIRATION IN SHANGHAI: EXPLANATORY THEORIES UNDERLYING A MODEL OF BEST PRACTICES [PDF]
Students in Shanghai, China, achieved the highest global scores in mathematics, science, and reading comprehension in the 2012 PISA assessment, outperforming education systems around the world.
Jean Désiré BANGA AMVÉNÉ
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A regular language R of finite words induces three repetition languages of infinite words: the language lim(R), which contains words with infinitely many prefixes in R, the language ∞ R, which contains words with infinitely many disjoint subwords in R, and the language R^ω, which contains infinite concatenations of words in R. Specifying behaviors, the
Kupferman, Orna, Leshkowitz, Ofer
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The essay is about Wisława Szymborska’s late poetry, especially the last volume, Wystarczy [Enough]. The poet’s frequent returns, repetitions, and various references to her earlier work are of particular importance.
Janina Abramowska
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Exhibition: Edvard Munch: The modern eye, Tate Modern, London (28 June 2012-14 October 2012)
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Spatial modulation of repetition blindness and repetition deafness
When two identical visual items are presented in rapid succession, people often fail to report the second instance when trying to recall both (e.g., Kanwisher, 1987). We investigated whether this temporal processing deficit is modulated by the spatial separation between the repeated stimuli within both audition and vision. In Experiment 1, lists of one
Soto-Faraco, S, Spence, C
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