Results 81 to 90 of about 313,114 (266)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Valeurs, compromis et polémiques
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2009 If the values of the conservation and the restoration of art have to be often reinterpreted in the face of certain cases of preservation of contemporary art (for example), how could it be when we talk about the conservation of ephemeral and performative ...
Anita Durand
doaj +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
De la palabra al género: un itinerario
Filología, 2014 La obra de Ana María Barrenechea se caracteriza por una atención a los modos de leer. Aquí se propone, más allá de las adhesiones disciplinares y a partir de unas determinadas experiencias de trabajo (es decir: de vida comunitaria) una relectura de la ...
Daniel Link
doaj
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Note sulla catastrofe del senso: Bernhard, Gargani, Derrida [PDF]
Kaiak, 2016 This essay examines some aspects of Thomas Bernhard’s works concerning the catastrophe of meaning, by the thought of two philosophers: Aldo Giorgio Gargani and Jacques Derrida. It is possible to escape from the ordinary procedures of criticizing the
Igor Pelgreffi
doaj
, 2020 A regular language R of finite words induces three repetition languages of infinite words: the language lim(R), which contains words with infinitely many prefixes in R, the language ∞ R, which contains words with infinitely many disjoint subwords in R, and the language R^ω, which contains infinite concatenations of words in R. Specifying behaviors, the
Kupferman, Orna, Leshkowitz, Ofer
openaire +3 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source