Results 81 to 90 of about 1,683,548 (326)

Load-Balanced Fractional Repetition Codes

, 2019
We introduce load-balanced fractional repetition (LBFR) codes, which are a strengthening of fractional repetition (FR) codes. LBFR codes have the additional property that multiple node failures can be sequentially repaired by downloading no more than one
Porter, Alexandra, Silas, Shashwat, Wootters, Mary   +2 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Validation of the ACGIH TLV for hand activity level in the OCTOPUS cohort: a two-year longitudinal study of carpal tunnel syndrome

Scandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: This study aimed to evaluate the risk of musculoskeletal disorders to the hand-wrist system. The American Conference of Governmental Industrial Hygienists (ACGIH) proposed threshold limit values (TLV©) based on hand activity level (HAL) and ...
Roberta Bonfiglioli, Stefano Mattioli, Tom J Armstrong, Francesca Graziosi, Francesco Marinelli, Andrea Farioli, Francesco S Violante   +6 more
doaj   +1 more source

Offset frequency dynamics and phase noise properties of a self-referenced 10 GHz Ti:sapphire frequency comb

, 2011
This paper shows the experimental details of the stabilization scheme that allows full control of the repetition rate and the carrier-envelope offset frequency of a 10 GHz frequency comb based on a femtosecond Ti:sapphire laser.
Bartels, Albrecht, Diddams, Scott A., Heinecke, Dirk C.   +2 more
core   +1 more source

Characterization of the aerosol produced by infrared femtosecond laser ablation of polyacrylamide gels for the sensitive inductively coupled plasma mass spectrometry detection of selenoproteins [PDF]

, 2009
A 2D high repetition rate femtosecondlaserablation strategy (2-mm wide lane) previously developed for the detection of selenoproteins in gel electrophoresis by inductively coupled plasma mass spectrometry was found to increase signal sensitivity by a ...
Alexis, Joël, Ballihaut, Guillaume, Claverie, Fanny, Donard, Olivier F. X., Fernandez Garcia, Beatriz, Lobinski, Ryszard, Mounicou, Sandra, Pécheyran, Christophe   +7 more
core   +2 more sources

Sentence repetition is a measure of children's language skills rather than working memory limitations

Developmental Science, 2014
Sentence repetition tasks are widely used in the diagnosis and assessment of children with language difficulties. This paper seeks to clarify the nature of sentence repetition tasks and their relationship to other language skills.
Marianne Klem, M. Melby-Lervåg, B. Hagtvet, S. Lyster, J. Gustafsson, C. Hulme   +5 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

La iconicidad de la reduplicación léxica en español [PDF]

Estudios Interlingüísticos, 2019
El objetivo del presente estudio consiste en examinar la motivación icónica de la reduplicación léxica en español. Como la reduplicación en distintas lenguas está asociada al fenómeno de la iconicidad, el presente artículo pretende averiguar si un tipo ...
Ewa Urbaniak
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source