Results 161 to 170 of about 1,761,722 (244)

In-Depth Satellitome Analyses of 37 Drosophila Species Illuminate Repetitive DNA Evolution in the Drosophila Genus. [PDF]

Genome Biol Evol, 2022
de Lima LG, Ruiz-Ruano FJ.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma. [PDF]

Front Cell Dev Biol
Zhang M, Dong S, Rao W, Mei S, Hu G, Liu L, Wang Z, Tang J.   +7 more
europepmc   +1 more source

RepeatProfiler: A pipeline for visualization and comparative analysis of repetitive DNA profiles. [PDF]

Mol Ecol Resour, 2021
Negm S, Greenberg A, Larracuente AM, Sproul JS.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes. [PDF]

Proc Natl Acad Sci U S A
Waisertreiger I, Ayele K, Elshaikh MH, Barlow JH.   +3 more
europepmc   +1 more source

Characterization of Repetitive DNA in Saccharum officinarum and Saccharum spontaneum by Genome Sequencing and Cytological Assays. [PDF]

Front Plant Sci, 2022
Wang K, Xiang D, Xia K, Sun B, Khurshid H, Esh AMH, Zhang H.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dynamics of repetitive DNA sequences over the course of evolution and intraspecific divergence of tetraploid goat-grass species Aegilops biuncialis vis. [PDF]

BMC Plant Biol
Badaeva ED, Razumova OV, González Franco MJ, Sokolova VM, Yurkina AI, Belousova MK, Chikida NN, Dragovich AY, Fisenko AV, Amosova AV, Surzhikov SA, Divashuk MG.   +11 more
europepmc   +1 more source

Blm helicase facilitates rapid replication of repetitive DNA sequences in early Drosophila development. [PDF]

Genetics, 2022
Ruchert JM, Brady MM, McMahan S, Lacey KJ, Latta LC, Sekelsky J, Stoffregen EP.   +6 more
europepmc   +1 more source