Results 21 to 30 of about 149,511 (282)

The Pontastacus leptodactylus (Astacidae) Repeatome Provides Insight Into Genome Evolution and Reveals Remarkable Diversity of Satellite DNA

Frontiers in Genetics, 2021
Pontastacus leptodactylus is a native European crayfish species found in both freshwater and brackish environments. It has commercial importance for fisheries and aquaculture industries. Up till now, most studies concerning P.
Ljudevit Luka Boštjančić, Lena Bonassin, Lucija Anušić, Leona Lovrenčić, Višnja Besendorfer, Ivana Maguire, Frederic Grandjean, Christopher M. Austin, Carola Greve, Alexander Ben Hamadou, Jelena Mlinarec   +10 more
doaj   +1 more source

Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping. [PDF]

PLoS Computational Biology, 2015
Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells' regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin ...
Xin Zeng, Bo Li, Rene Welch, Constanza Rojo, Ye Zheng, Colin N Dewey, Sündüz Keleş   +6 more
doaj   +1 more source

Comparative repeatome analysis on Triatoma infestans Andean and Non-Andean lineages, main vector of Chagas disease. [PDF]

PLoS ONE, 2017
Triatoma infestans is the most important Chagas disease vector in South America. Two main evolutionary lineages, named Andean and non-Andean, have been recognized by geographical distribution, phenetic and genetic characteristics.
Sebastián Pita, Francisco Panzera, Pablo Mora, Jesús Vela, Ángeles Cuadrado, Antonio Sánchez, Teresa Palomeque, Pedro Lorite   +7 more
doaj   +1 more source

Directed PCR-free engineering of highly repetitive DNA sequences

BMC Biotechnology, 2011
Background Highly repetitive nucleotide sequences are commonly found in nature e.g. in telomeres, microsatellite DNA, polyadenine (poly(A)) tails of eukaryotic messenger RNA as well as in several inherited human disorders linked to trinucleotide repeat ...
Preissler Steffen, Scior Annika, Koch Miriam, Deuerling Elke   +3 more
doaj   +1 more source

DeepGRP: engineering a software tool for predicting genomic repetitive elements using Recurrent Neural Networks with attention

Algorithms for Molecular Biology, 2021
Background Repetitive elements contribute a large part of eukaryotic genomes. For example, about 40 to 50% of human, mouse and rat genomes are repetitive. So identifying and classifying repeats is an important step in genome annotation.
Fabian Hausmann, Stefan Kurtz
doaj   +1 more source

Evolutionary rates and patterns for human transcription factor binding sites derived from repetitive DNA

BMC Genomics, 2008
Background The majority of human non-protein-coding DNA is made up of repetitive sequences, mainly transposable elements (TEs). It is becoming increasingly apparent that many of these repetitive DNA sequence elements encode gene regulatory functions ...
McDonald John F, Landsman David, Mariño-Ramírez Leonardo, Polavarapu Nalini, Jordan I King   +4 more
doaj   +1 more source

The case for not masking away repetitive DNA

Mobile DNA, 2018
In the course of analyzing whole-genome data, it is common practice to mask or filter out repetitive regions of a genome, such as transposable elements and endogenous retroviruses, in order to focus only on genes and thus simplify the results.
R. Keith Slotkin
doaj   +1 more source

Analysis of repeat elements in the Pristionchus pacificus genome reveals an ancient invasion by horizontally transferred transposons

BMC Genomics, 2022
Background Repetitive sequences and mobile elements make up considerable fractions of individual genomes. While transposition events can be detrimental for organismal fitness, repetitive sequences form an enormous reservoir for molecular innovation.
Marina Athanasouli, Christian Rödelsperger   +1 more
doaj   +1 more source

Normalization of genomic DNA using duplex-specific nuclease

BioTechniques, 2010
An application of duplex-specific nuclease (DSN) normalization technology to whole-genome shotgun sequencing of genomes with a large proportion of repetitive DNA is described.
Irina Shagina, Ekaterina Bogdanova, Ilgar Z. Mamedov, Yury Lebedev, Sergey Lukyanov, Dmitry Shagin   +5 more
doaj   +1 more source

Epigenetics and triplet repeat neurological diseases

Frontiers in Neurology, 2015
The term ‘junk DNA’ has been reconsidered following the delineation of the functional significance of repetitive DNA regions. Typically associated with centromeres and telomeres, DNA repeats are found in nearly all organisms throughout their genomes ...
Sathiji eNageshwaran, Richard eFestenstein   +1 more
doaj   +1 more source