Results 31 to 40 of about 1,761,722 (244)

Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping. [PDF]

open access: yesPLoS Computational Biology, 2015
Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells' regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin ...
Xin Zeng   +6 more
doaj   +1 more source

Molecular cytogenetic mapping of Cucumis sativus and C. melo using highly repetitive DNA sequences [PDF]

open access: yes, 2010
Chromosomes often serve as one of the most important molecular aspects of studying the evolution of species. Indeed, most of the crucial mutations that led to differentiation of species during the evolution have occurred at the chromosomal level ...
Jong, J.H.S.G.M., de   +6 more
core   +1 more source

Repetitive Sequences in Plant Nuclear DNA: Types, Distribution, Evolution and Function

open access: yesGenomics, Proteomics & Bioinformatics, 2014
Repetitive DNA sequences are a major component of eukaryotic genomes and may account for up to 90% of the genome size. They can be divided into minisatellite, microsatellite and satellite sequences.
Shweta Mehrotra, Vinod Goyal
doaj   +1 more source

Directed PCR-free engineering of highly repetitive DNA sequences

open access: yesBMC Biotechnology, 2011
Background Highly repetitive nucleotide sequences are commonly found in nature e.g. in telomeres, microsatellite DNA, polyadenine (poly(A)) tails of eukaryotic messenger RNA as well as in several inherited human disorders linked to trinucleotide repeat ...
Preissler Steffen   +3 more
doaj   +1 more source

DeepGRP: engineering a software tool for predicting genomic repetitive elements using Recurrent Neural Networks with attention

open access: yesAlgorithms for Molecular Biology, 2021
Background Repetitive elements contribute a large part of eukaryotic genomes. For example, about 40 to 50% of human, mouse and rat genomes are repetitive. So identifying and classifying repeats is an important step in genome annotation.
Fabian Hausmann, Stefan Kurtz
doaj   +1 more source

Analysis of a c0t-1 library enables the targeted identification of minisatellite and satellite families in Beta vulgaris [PDF]

open access: yes, 2010
Zakrzewski F, Wenke T, Holtgräwe D, Weisshaar B, Schmidt T. Analysis of a c0t-1 library enables the targeted identification of minisatellite and satellite families in Beta vulgaris. BMC Plant Biology.
Zakrzewski, Falk   +14 more
core   +1 more source

Evolutionary rates and patterns for human transcription factor binding sites derived from repetitive DNA

open access: yesBMC Genomics, 2008
Background The majority of human non-protein-coding DNA is made up of repetitive sequences, mainly transposable elements (TEs). It is becoming increasingly apparent that many of these repetitive DNA sequence elements encode gene regulatory functions ...
McDonald John F   +4 more
doaj   +1 more source

A comparative investigation of nuclear DNA content and its phenotypic impacts in Silene marizii and S. latifolia [PDF]

open access: yes, 2008
Considerable variation exists both within and between species in nuclear DNA content. Despite there being no obvious functional role for much of this DNA, many studies have reported phenotypic correlations with genome size at various taxonomic levels ...
Looseley, Mark E
core   +2 more sources

The case for not masking away repetitive DNA

open access: yesMobile DNA, 2018
In the course of analyzing whole-genome data, it is common practice to mask or filter out repetitive regions of a genome, such as transposable elements and endogenous retroviruses, in order to focus only on genes and thus simplify the results.
R. Keith Slotkin
doaj   +1 more source

Investigation of distal repetitive sequences in the genus allium [PDF]

open access: yes, 2009
PhDThe telomere is a DNA/protein structure required to maintain the ends of linear chromosomes. Usually the DNA component comprises a highly conserved tandemly repeated minisatellite sequence.
Chester, Michael
core   +4 more sources

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