Results 111 to 120 of about 71,813 (221)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

open access: yesAdvanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou   +14 more
wiley   +1 more source

Evaluation of Each Three <i>Entamoeba histolytica</i>- and <i>Strongyloides stercoralis</i>-Specific Real-Time PCR Assays Applying Test Comparisons Without Reference Standards. [PDF]

open access: yesMicroorganisms
Zautner AE   +13 more
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

open access: yesAdvanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang   +10 more
wiley   +1 more source

Related polypeptides are encoded by Drosophila F elements, I factors, and mammalian L1 sequences.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1987
P. D. Di Nocera, G. Casari
semanticscholar   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

open access: yesAdvanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen   +11 more
wiley   +1 more source

Insights into the architecture of earthworm metallothionein genes, powered by long-read genomics and transcriptomics. [PDF]

open access: yesNAR Genom Bioinform
Karpov MA   +6 more
europepmc   +1 more source

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