Results 81 to 90 of about 116,375 (241)
The genomes of two key bumblebee species with primitive eusocial organization [PDF]
Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies.
Amdam, Gro V.+143 more
core +14 more sources
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen+16 more
wiley +1 more source
In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization [PDF]
The origin recognition complex (ORC) of Saccharomyces cerevisiae binds origin DNA and cooperates with Cdc6 and Cdt1 to load the replicative helicase MCM2–7 onto DNA. Helicase loading involves two MCM2–7 hexamers that assemble into a double hexamer around
A. Fernandez-Cid+47 more
core +1 more source
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
A comprehensive study of Z-DNA density and its evolutionary implications in birds
Background Z-DNA, a left-handed helical form of DNA, plays a significant role in genomic stability and gene regulation. Its formation, associated with high GC content and repetitive sequences, is linked to genomic instability, potentially leading to ...
Yu-Ren Wang+10 more
doaj +1 more source
Capturing the ‘ome’ : the expanding molecular toolbox for RNA and DNA library construction [PDF]
All sequencing experiments and most functional genomics screens rely on the generation of libraries to comprehensively capture pools of targeted sequences.
Boone, Morgane+2 more
core +2 more sources
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source
The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong+8 more
wiley +1 more source
Designing the Self‐Assembly of Disordered Materials Via Color Frustration
What if disorder can be designed? This work introduces a strategy to self‐assemble amorphous materials by designing bonding rules for patchy particles that suppress crystallinity and promote frustration. The designer particles nucleate a network of dodecahedral cages from the liquid, yielding a novel equilibrium amorphous phase. This approach redefines
Andreas Neophytou+2 more
wiley +1 more source