Results 91 to 100 of about 878,509 (289)

A preliminary annotated checklist and evaluation of the diversity of the Chrysomelidae (Coleoptera) of the Baja California peninsula, Mexico [PDF]

, 2005
A preliminary annotated checklist of the Chrysomelidae of the Baja California peninsula, Mexico is presented based on literature records and the examination of approximately 16,000 chrysomelid specimens.
Andrews, Fred G., Gilbert, Arthur J.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A replacement name for the endemic Rattus (Muridae, Mammalia) of the island of Obi, Indonesia

Records of the Australian Museum
The name Rattus obiensis Fabre, Portela Miguez, Holden, Fitriana, Semiadi, Musser, & Helgen, was recently applied to a newly discovered species of Rattus known to date only from the Moluccan island of Obi in Indonesia.
Pierre-Henri Fabre, Roberto Portela Miguez, Mary Ellen Holden, Yuli S. Fitriana, Gono Semiadi, Guy G. Musser, Kristofer M. Helgen   +6 more
doaj   +1 more source

Description de deux espèces de Wapitiphyllum McLEAN, R.A. et PEDDER, A.E.H., 1984 récoltées dans le Frasnien de Huccorgne, au bord nord du Bassin de Namur [PDF]

, 1986
In the middle part of the Frasnian at Huccorgne, on the northern border of the Namur Synclinorium, the genus Wapitiphyllum McLEAN. R.A. and PEDDER, A.E.H., 1984 is represented by two species unknown up to now elsewhere in Belgium.
Coen-Aubert, M.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Showing the destination of hypertext links: a new approach for Guide [PDF]

, 1992
All hypertext systems have a kind of button which can be selected interactively by the user to obtain further information. This paper is concerned with how to show the user the further information when the button is selected.
da Gracca Campos Pimentel, Maria
core   +1 more source

Characterizations of pretameness and the Ord-cc

, 2017
It is well known that pretameness implies the forcing theorem, and that pretameness is characterized by the preservation of the axioms of $\mathsf{ZF}^-$, that is $\mathsf{ZF}$ without the power set axiom, or equivalently, by the preservation of the ...
Holy, Peter, Krapf, Regula, Schlicht, Philipp   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source