Results 1 to 10 of about 673,231 (163)

Non-model model organisms [PDF]

open access: yesBMC Biology, 2017
Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to ...
James J. Russell   +18 more
doaj   +5 more sources

Metabolomic Studies for the Evaluation of Toxicity Induced by Environmental Toxicants on Model Organisms

open access: yesMetabolites, 2021
Environmental pollution causes significant toxicity to ecosystems. Thus, acquiring a deeper understanding of the concentration of environmental pollutants in ecosystems and, clarifying their potential toxicities is of great significance.
Hyung Min Kim, Jong Seong Kang
doaj   +3 more sources

miR-29a/b1 Regulates the Luteinizing Hormone Secretion and Affects Mouse Ovulation

open access: yesFrontiers in Endocrinology, 2021
miR-29a/b1 was reportedly involved in the regulation of the reproductive function in female mice, but the underlying molecular mechanisms are not clear.
Yang Guo   +19 more
doaj   +1 more source

Skin-to-blood pH shift triggers metabolome and proteome global remodelling in Staphylococcus epidermidis

open access: yesFrontiers in Microbiology, 2022
Staphylococcus epidermidis is one of the most common bacteria of the human skin microbiota. Despite its role as a commensal, S. epidermidis has emerged as an opportunistic pathogen, associated with 80% of medical devices related infections.
Luis Gafeira Gonçalves   +5 more
doaj   +1 more source

Protocols for transgenesis at a safe harbor site in the Xenopus laevis genome using CRISPR-Cas9

open access: yesSTAR Protocols, 2023
Summary: We have established a new transgenesis protocol based on CRISPR-Cas9, “New and Easy Xenopus Transgenesis (NEXTrans),” and identified a novel safe harbor site in African clawed frogs, Xenopus laevis.
Yuki Shibata   +3 more
doaj   +1 more source

Editorial: Model organisms in toxicology. [PDF]

open access: yesFront Toxicol
Aschner M, Dasmahapatra AK, Muriana A.
europepmc   +2 more sources

A simple and rapid protein purification method based on cell-surface display of SUMO-fused recombinant protein and Ulp1 protease

open access: yesAMB Express, 2020
The development of novel methods for highly efficient protein purification remains a research focus in the biotechnology field because conventional purification approaches, including affinity purification, gel filtration, and ion-exchange chromatography,
Xiao-Feng Zhou   +12 more
doaj   +1 more source

A Fetching Model Organism [PDF]

open access: yesCell, 2006
The creation of the domestic dog and its many breeds has been an ongoing experiment in the rapid evolution of form and function. Now, advances in genomics have made Canis familiaris genetically tractable and poised to offer insights into evolution, development, and behavior.
Neff, Mark W., Rine, Jasper
openaire   +2 more sources

Acoustic Characterization for The Feeding Activities of Haliotis discus Hannai

open access: yesApplied Sciences, 2023
In order to analyze the sound production mechanism and the acoustic characteristics of Haliotis discus hannai during feeding, this paper proposes a multi-source information fusion approach combining passive acoustics with videos.
Hongyue Lin   +6 more
doaj   +1 more source

A novel multimeric sCD19‐streptavidin fusion protein for functional detection and selective expansion of CD19‐targeted CAR‐T cells

open access: yesCancer Medicine, 2022
Background CARs are engineered receptors comprising an immunoglobulin single‐chain variable fragment (scFv) that identifies and binds to the target antigen, a transmembrane domain, and an intracellular T‐cell signaling domain.
Hui Lian   +10 more
doaj   +1 more source

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