Results 21 to 30 of about 735,742 (300)

Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly

open access: yesFrontiers in Immunology, 2019
Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such as infectious diseases and cancer.
Pengcheng Chen   +19 more
doaj   +1 more source

Improvement of Detection Method of Pasteurella pneumotropica and Its Medical Elimination in Mice

open access: yesShiyan dongwu yu bijiao yixue, 2021
ObjectiveTo modify the method for sensitive detection of Pasteurella pneumotropica in mice in routine monitoring, and to explore the feasibility of medical elimination in Pasteurella pneumotropica infected mice.MethodsThe Pasteurella pneumotropica were ...
ZHANG Tao   +3 more
doaj   +1 more source

Models of Organic Organization in Montpellier Vitalism [PDF]

open access: yesEarly Science and Medicine, 2017
The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot).
openaire   +2 more sources

ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis

open access: yesMolecular Therapy: Nucleic Acids, 2017
Human bladder cancer (BC) is the fourth most common cancer in the United States. Investigation of the strategies aiming to elucidate the tumor growth and metastatic pathways in BC is critical for the management of this disease.
Junlan Zhu   +11 more
doaj   +1 more source

Evolving strategies for single-celled organisms in multi-nutrient environments [PDF]

open access: yes, 2015
When micro-organisms are in environments with multiple nutrients, they often preferentially utilise one first. A second is only utilised once the first is exhausted. Such a two-phase growth pattern is known as diauxic growth.
David J. Barnes   +3 more
core   +1 more source

miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone

open access: yesiScience, 2022
Summary: Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling.
Liping Ouyang   +12 more
doaj   +1 more source

Transcriptomic congruence analysis for evaluating model organisms [PDF]

open access: yes, 2023
Model organisms are instrumental substitutes for human studies to expedite basic, translational, and clinical research. Despite their indispensable role in mechanistic investigation and drug development, molecular congruence of animal models to humans ...
Tanbin Rahman   +27 more
core   +1 more source

Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice

open access: yesNeural Plasticity, 2017
Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness.
Hua Yang   +9 more
doaj   +1 more source

Comparative Genomic and Pan-Genomic Characterization of Staphylococcus epidermidis From Different Sources Unveils the Molecular Basis and Potential Biomarkers of Pathogenic Strains

open access: yesFrontiers in Microbiology, 2021
Coagulase-negative Staphylococcus (CoNS) is the most common pathogen causing traumatic endophthalmitis. Among which, Staphylococcus epidermidis is the most common species that colonizes human skin, eye surfaces, and nasal cavity.
Shudan Lin   +12 more
doaj   +1 more source

A model of intracellular organization [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
Almost everything we know about biological chemistry comes from experiments on dilute samples of macromolecules (proteins, DNA, RNA, polysaccharides, etc.). By “dilute,” I mean macromolecular concentrations of 10 g per liter or less. Such conditions are astonishingly different from those inside living cells (1, 2).
openaire   +2 more sources

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