Results 11 to 20 of about 1,433,700 (300)
Background CARs are engineered receptors comprising an immunoglobulin single‐chain variable fragment (scFv) that identifies and binds to the target antigen, a transmembrane domain, and an intracellular T‐cell signaling domain.
Hui Lian +10 more
doaj +1 more source
Both PD1/PD-L1 and CD47 blockades have demonstrated limited activity in most subtypes of NHL save NK/T-cell lymphoma. The hemotoxicity with anti-CD47 agents in the clinic has been speculated to account for their limitations. Herein we describe a first-in-
Hang Ke +15 more
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A porous prolate-spheroidal model for ciliated micro-organisms [PDF]
A fluid-mechanical model is developed for representing the mechanism of propulsion of a finite ciliated micro-organism having a prolate-spheroidal shape.
Keller, Stuart R., Wu, Theodore Y.
core +1 more source
Adhesion G protein-coupled receptor A1 (ADGRA1, also known as GPR123) belongs to the G protein-coupled receptors (GPCRs) family and is well conserved in the vertebrate lineage.
Xiao-Hong Zhang +12 more
doaj +1 more source
Brown Algal Model Organisms [PDF]
Model organisms are extensively used in research as accessible and convenient systems for studying a particular area or question in biology. Traditionally, only a limited number of organisms have been studied in detail, but modern genomic tools are enabling researchers to extend beyond the set of classical model organisms to include novel species from
Coelho, Susana M., Cock, J. Mark
openaire +4 more sources
Multiple phase transitions in an agent-based evolutionary model with neutral fitness [PDF]
Null models are crucial for understanding evolutionary processes such as speciation and adaptive radiation. We analyse an agent-based null model, considering a case without selection—neutral evolution—in which organisms are defined only by phenotype ...
Bahar, Sonya +2 more
core +2 more sources
Improvement of Detection Method of Pasteurella pneumotropica and Its Medical Elimination in Mice
ObjectiveTo modify the method for sensitive detection of Pasteurella pneumotropica in mice in routine monitoring, and to explore the feasibility of medical elimination in Pasteurella pneumotropica infected mice.MethodsThe Pasteurella pneumotropica were ...
ZHANG Tao +3 more
doaj +1 more source
Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such as infectious diseases and cancer.
Pengcheng Chen +19 more
doaj +1 more source
Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin +3 more
core +1 more source
Human bladder cancer (BC) is the fourth most common cancer in the United States. Investigation of the strategies aiming to elucidate the tumor growth and metastatic pathways in BC is critical for the management of this disease.
Junlan Zhu +11 more
doaj +1 more source

