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, 2020 Model organisms are extensively used in research as accessible and convenient systems for studying a particular area or question in biology. Traditionally, only a limited number of organisms have been studied in detail, but modern genomic tools are ...
Cock, J. Mark +3 more
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Metabolic network modeling with model organisms [PDF]
Current Opinion in Chemical Biology, 2017 Flux balance analysis (FBA) with genome-scale metabolic network models (GSMNM) allows systems level predictions of metabolism in a variety of organisms. Different types of predictions with different accuracy levels can be made depending on the applied experimental constraints ranging from measurement of exchange fluxes to the integration of gene ...
Yilmaz, L. Safak, Walhout, Albertha J M
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Model Organisms in Plant Genetics [PDF]
, 2022 Model plants are required for research when targeted plant species are difficult to study or when research material is unavailable. Importantly, knowledge gained from model plants can be generally translated to other related plant species because many ...
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Microbiology Spectrum, 2022 Acanthamoeba species are among the most ubiquitous protists that are widespread in soil and water and act as both a replicative niche and vectors for dispersal. They are the most important human intracellular pathogens, causing Acanthamoeba keratitis (AK)
Xiaobin Gu +11 more
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Developmental genetics with model organisms
, 2022 In Darwin's and Mendel's times, researchers investigated a wealth of organisms, chosen to solve particular problems for which they seemed especially well suited. Later, a focus on a few organisms, which are accessible to systematic genetic investigations,
Nüsslein-Volhard, Christiane +3 more
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Model organisms as scientific representations [PDF]
, 2023 In this paper, I argue that model organisms (MOs) function as representations of other organisms, in the same way in which scientific models function as representations of their targets. This offers a response to the question of how we justify inferences
Sartori, Lorenzo
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Brain SciencesBackground: GABAergic signaling plays a crucial role in modulating neuronal proliferation, migration, and the formation of neural network connections. The termination of GABA transmission primarily occurs through the action of GABA transporter 1 (GAT1 ...
Weitong Liu +9 more
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Frontiers in Molecular Neuroscience, 2022 Rodents have been the dominant animal models in neurobiology and neurological disease research over the past 60 years. The prevalent use of rats and mice in neuroscience research has been driven by several key attributes including their organ physiology ...
Elizabeth M. Haynes +6 more
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Model Organisms are Not (Theoretical) Models [PDF]
, 2015 Many biological investigations are organized around a small group of species, often referred to as “model organisms”, such as the fruit fly Drosophila melanogaster.
Levy, Arnon, Currie, Adrian
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Life histories in groundwater organisms
, 2023 In this chapter, we explore the current state of life history research in groundwater fauna, including a brief review of life history evolution, life history traits, and life table variables.
Oana Teodora Moldovan +9 more
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