Results 31 to 40 of about 193,735,207 (244)

Explainable temporal graph-based CNNs for predicting hip replacement risk using EHR data

BMJ Digital Health & AI
Objective To develop and compare four explainable artificial intelligence methods to visualise the influence of electronic health records (EHRs) on predicting hip replacement risk.Methods and analysis We used a pretrained temporal graph-based ...
David Wong, Philip G Conaghan, Andrew Clegg, Sarah R Kingsbury, Samuel D Relton, Zoe Hancox   +5 more
doaj   +1 more source

The Importance of Root Interactions in Field Bean/Triticale Intercrops

Plants, 2020
To highlight the contribution of belowground interactions to biomass and N and P yields, field bean and triticale were grown in a P-poor soil as sole crops and as replacement intercrops at two N levels.
Dayana N. Esnarriaga, Marco Mariotti, Roberto Cardelli, Iduna Arduini   +3 more
doaj   +1 more source

Ovariectomy reduces cholinergic modulation of excitatory synaptic transmission in the rat entorhinal cortex.

PLoS ONE, 2022
Estrogens are thought to contribute to cognitive function in part by promoting the function of basal forebrain cholinergic neurons that project to the hippocampus and cortical regions including the entorhinal cortex.
Ariel A Batallán Burrowes, Olayemi Joseph Olajide, Isabella A Iasenza, Waqqas M Shams, Francis Carter, C Andrew Chapman   +5 more
doaj   +1 more source

Replacement of plant communities altered soil bacterial diversity and structure rather than the function in similar habitats of the Yellow River Delta, China

Ecological Indicators, 2023
Convergent evolution in plants has important roles in understanding the coexistence of species and the construction of communities in the same habitat. However, evidence that determines whether this phenomenon also occurs in soil bacteria is lacking.
Xue Mo, Ye Song, Feijie Chen, Chong You, Desheng Li, Fude Liu   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Transcatheter versus surgical aortic-valve replacement in high-risk patients. [PDF]

, 2011
BACKGROUND: The use of transcatheter aortic-valve replacement has been shown to reduce mortality among high-risk patients with aortic stenosis who are not candidates for surgical replacement.
Makkar, Raj R, Samir Kapadia, Dewey, Todd, Pichard, Augusto D, Mack, Michael J, Vinod H. Thourani, Duolao Wang, Smith, Craig R, Webb, John G, Babaliaros, Vasilis, Moses, Jeffrey W, D. Craig Miller, Jeffrey W. Moses, Wang, Duolao, Craig R. Smith, Mathew Williams, Todd Dewey, Miller, D Craig, Michael J. Mack, John G. Webb, William N. Anderson, Tuzcu, E Murat, Thourani, Vinod H, Raj R. Makkar, Gregory P. Fontana, Svensson, Lars G, Kapadia, Samir, E. Murat Tuzcu, Paul Corso, Martin B. Leon, Williams, Mathew, Stuart J. Pocock, Bavaria, Joseph E, MD, Howard C. Herrmann, Augusto D. Pichard, Lars G. Svensson, Pocock, Stuart J, Jodi J. Akin, Joseph E. Bavaria, Fontana, Gregory P, Akin, Jodi J, Corso, Paul, Bavaria, Joseph E, Leon, Martin B, Herrmann, Howard C, PARTNER Trial Investigators, Anderson, William N, Vasilis Babaliaros   +47 more
core   +1 more source

Effect of bio-enriched paddy straw compost on reduction of chemical fertilisers in rice (Oryza sativa) – wheat (Triticum aestivum) cropping system

The Indian Journal of Agricultural Sciences
Due to increasing awareness on the benefit of organic farming for sustainable ecosystem, there is an increase in area of organic cultivation and demand of organic inputs.
VELLAICHAMY MAGESHWARAN, ANUPRIYA YADAV, ADARSH KUMAR, ALOK KUMAR SRIVASTAVA   +3 more
doaj   +1 more source

Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning

Cell Reports, 2019
Summary: Parkinson’s disease causes the most profound loss of the aldehyde dehydrogenase 1A1-positive (ALDH1A1+) nigrostriatal dopaminergic neuron (nDAN) subpopulation.
Junbing Wu, Justin Kung, Jie Dong, Lisa Chang, Chengsong Xie, Ahsan Habib, Sarah Hawes, Nannan Yang, Vivian Chen, Zhenhua Liu, Rebekah Evans, Bo Liang, Lixin Sun, Jinhui Ding, Jia Yu, Sara Saez-Atienzar, Beisha Tang, Zayd Khaliq, Da-Ting Lin, Weidong Le, Huaibin Cai   +20 more
doaj   +1 more source

FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling

BMC Biology, 2020
Background The formation of supernumerary teeth is an excellent model for studying the molecular mechanisms that control stem/progenitor cell homeostasis needed to generate a renewable source of replacement cells and tissues.
Jingyi Wu, Ye Tian, Lu Han, Chao Liu, Tianyu Sun, Ling Li, Yanlei Yu, Bikash Lamichhane, Rena N. D’Souza, Sarah E. Millar, Robb Krumlauf, David M. Ornitz, Jian Q. Feng, Ophir Klein, Hu Zhao, Fuming Zhang, Robert J. Linhardt, Xiaofang Wang   +17 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source