Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Transitions from AFDC to SSI Prior to Welfare Reform – Policy Brief [PDF]
The Supplemental Security Income (SSI) and Temporary Assistance for Needy Families (TANF) programs serve overlapping target groups. SSI serves adults and children with disabilities from low-income families, while TANF serves low-income families with ...
Chan, Erica +2 more
core +2 more sources
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
CREATING FIRM VALUE: LINKING DEMAND UNCERTAINTY, ADAPTATION VERSUS REPLACEMENT INVESTMENTS, AND RISK
Real assets investment can relate to real options. This study aims at analysing the effect of demand uncertainty on replacement investment and adaptation investment supported by manager’s attitude towards risk and the effect of each investment type on ...
Nur Khusniyah Indrawati
doaj +1 more source
Adapting ACME to the database caching environment : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Information Systems at Massey University [PDF]
The field of database cache replacement has seen a great many replacement policies presented in the past few years. As the challenge to find the optimal replacement policy continues, new methods and techniques of determining cache victims have been ...
Riaz-ud-Din, Faizal
core
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
A discounted model for a repairable system with continuous state space [PDF]
We examine repairable systems with a continous state space and partial repair options, carried out at fixed times $n=1,2,...$. Every time interval $[n,n+1)$ there is a manufacturing cost and a repair cost.
Bruns, P.B.
core +2 more sources
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
A Copula-based Maintenance Modeling for Parallel Systems with Non-self Announcing Failures and Dependent Components [PDF]
Based on a copula function this paper addresses a maintenance scheduling problem for parallel systems whose components are dependent and their failures are detected only by inspections. To carry out preventive maintenance actions, the decision process is
Reza Ahmadi
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source

