G3: Genes, Genomes, Genetics, 2020 Homologous recombination is an important mechanism for genome integrity maintenance, and several homologous recombination genes are mutated in various cancers and cancer-prone syndromes.
Daniele Novarina +6 more
doaj +1 more source
Antimicrobial Resistance and Infection Control, 2022 Background Logistical and economic barriers hamper community-level surveillance for antimicrobial-resistant bacteria in low-income countries. Latrines are commonly used in these settings and offer a low-cost source of surveillance samples. It is unclear,
Sylvia Omulo +4 more
doaj +1 more source
Incubator-independent cell-culture perfusion platform for continuous long-term microelectrode array electrophysiology and time-lapse imaging [PDF]
Royal Society Open Science, 2015 Most in vitro electrophysiology studies extract information and draw conclusions from representative, temporally limited snapshot experiments. This approach bears the risk of missing decisive moments that may make a difference in our understanding of ...
Dirk Saalfrank +8 more
doaj +1 more source
Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]
, 1967 Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M. +35 more
core +2 more sources
Antimalarial therapy selection for quinolone resistance among Escherichia coli in the absence of quinolone exposure, in tropical South America. [PDF]
PLoS ONE, 2008 BackgroundBacterial resistance to antibiotics is thought to develop only in the presence of antibiotic pressure. Here we show evidence to suggest that fluoroquinolone resistance in Escherichia coli has developed in the absence of fluoroquinolone use ...
Ross J Davidson +13 more
doaj +1 more source
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. [PDF]
, 2017 Broad-scale protein-protein interaction mapping is a major challenge given the cost, time, and sensitivity constraints of existing technologies. Here, we present a massively multiplexed yeast two-hybrid method, CrY2H-seq, which uses a Cre recombinase ...
Bartlett, Anna +12 more
core +2 more sources
Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae. [PDF]
PLoS ONE, 2017 Pseudomonas syringae pv. actinidiae (Psa), the causal agent of kiwifruit canker, is one of the most devastating plant diseases of recent times. We have generated two mini-Tn5-based random insertion libraries of Psa ICMP 18884.
Carl H Mesarich +8 more
doaj +1 more source
Apparatus for rapid replica plating in rhizosphere studies [PDF]
Applied Microbiology, 1966 Rhizosphere investigations are restricted by the sheer number of cultures that must be handled in the multitude of different tubed media needed to characterize each isolate. A current rhizosphere study called for the use of 25 different diagnostic media with each of hundreds of isolates, a burdensome and laborious problem. Moreover, the replica plating
J L, Neal +3 more
openaire +2 more sources
Using cellular fitness to map the structure and function of a major facilitator superfamily effluxer. [PDF]
, 2017 The major facilitator superfamily (MFS) effluxers are prominent mediators of antimicrobial resistance. The biochemical characterization of MFS proteins is hindered by their complex membrane environment that makes in vitro biochemical analysis challenging.
Bennett, Matthew R +5 more
core +2 more sources
Alternative Replica Plating Technique [PDF]
Applied and Environmental Microbiology, 1977 A new technique for picking bacterial colonies and a new type of replicator are described.
openaire +2 more sources