Results 221 to 230 of about 20,760 (271)

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

µCodes: A Universal Grid Platform for Microscale Mapping, Microscopy Navigation, and Multimodal Imaging. [PDF]

Small
Valipour A, Ha J, Housley SN.
europepmc   +1 more source

Defining APOBEC-induced mutation signatures and modifying activities in yeast. [PDF]

Methods Enzymol
Mertz TM, Kockler ZW, Coxon M, Cordero C, Raval AK, Brown AJ, Harcy V, Gordenin DA, Roberts SA.   +8 more
europepmc   +1 more source

A non-hypothesis-driven practical laboratory activity on functional metagenomics: "fishing" protein-coding DNA sequences from microbiomes. [PDF]

Front Bioeng Biotechnol
Morra M, Marradi D, Gandini L, Ivagnes V, Ottolini G, Bovio A, Jabali G, Maraschi L, Dada IA, Chawanda TV, Gorla M, Tarasiuk O, Mocchetti C, Soluri MF, Boccafoschi F, Sblattero D, Cotella D.   +16 more
europepmc   +1 more source

CRISPR-Cas targeting in Haloferax volcanii promotes within-species gene exchange by triggering homologous recombination

Choudhary DK, Turgeman-Grott I, Robinzon S, Gophna U.   +3 more
europepmc   +1 more source

Mutations altering the DNA binding domains of the human RAD52 protein exert distinct effects on homologous recombination repair in Saccharomyces cerevisiae. [PDF]

G3 (Bethesda)
Manthey GM, Wolf EW, Xu J, Negritto MC, Bouley RA, Petreaca RC, Bailis AM.   +6 more
europepmc   +1 more source

The engineering toolbox of Parageobacillus thermoglucosidasius. [PDF]

Appl Microbiol Biotechnol
Millgaard M, Escher B, Pogrebnyakov I, Nielsen AT.   +3 more
europepmc   +1 more source

Facile Fabrication of Hierarchical Structured Anodic Aluminum Oxide Molds for Large-Scale Production of Superhydrophobic Polymer Films. [PDF]

Polymers (Basel)
Balasankar A, Venkatesan R, Jeong DY, Oh TH, Kim SC, Vetcher AA, Ramasundaram S.   +6 more
europepmc   +1 more source

Fitness effects of antimicrobial resistance genes in changing environments

Escudero JA, Hipólito A, García-Pastor L, von Strempel A, Weiss A, Sastre-Dominguez J, Vergara E, Alvarez J, Fuentes-Hernández A, Peña-Miller R, Millan AS, Stecher B.   +11 more
europepmc   +1 more source

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Replica plating of cultured mammalian cells

Somatic Cell Genetics, 1981
A simple device is described which permits the replica plating of lymphocytes as well as substrate adherent fibroblasts. The replica plating device consists of an 8 X 12 array of cotton-tipped swabs (Q-tips). The principle of the replica plating system involves the use of an array of absorbent cotton-tipped swabs to transfer nonadherent lymphocytes (or
R J, Klebe, P J, Sasser, R C, Schoen
exaly   +3 more sources