Results 51 to 60 of about 30,672 (266)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Replication Database: Documenting the Replicability of Psychological Science [PDF]
In psychological science, replicability—repeating a study with a new sampleachieving consistent results (Parsons et al., 2022)—is critical for affirming the validity of scientific findings. Despite its importance, replication efforts are few and far between in psychological science with many attempts failing to corroborate past findings. This scarcity,
Lukas Röseler +96 more
openaire +13 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Compression by replication [PDF]
A recently introduced inference method based on system replication and an online message passing algorithm is employed to complete a previously suggested compression scheme based on a nonlinear perceptron. The algorithm is shown to approach the information theoretical bounds for compression as the number of replicated systems increases, offering ...
Alamino, Roberto C. +2 more
openaire +2 more sources
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Systematic Review of Eye-Tracking Technology in Second Language Research
Eye-tracking has become increasingly popular in second language (L2) research. In this study, we systematically reviewed 111 eye-tracking studies published in 17 L2 journals to explore the application and replicability of eye-tracking technology in L2 ...
Xin Hu, Vahid Aryadoust
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Restricted access data in the neurosciences: Are the restrictions always justified?
Richard Lathe
doaj +1 more source
Taxonomy lays the foundations for the study of biodiversity and its conservation. Procrustean geometric morphometrics (GMM) is a most common technique for the taxonomic assessment of phenotypic population differences.
Andrea Cardini
doaj +1 more source

