Results 71 to 80 of about 1,173,714 (339)

Replicability of data collected for empirical estimation of relative pollen productivity [PDF]

open access: yes, 2016
The effects of repeated survey and fieldwork timing on data derived from a recently proposed standard field methodology for empirical estimation of relative pollen productivity (RPP) have been tested.
Bunting, M. Jane   +2 more
core   +2 more sources

Cross-cohort replicability and generalizability of connectivity-based psychometric prediction patterns

open access: yesNeuroImage, 2022
An increasing number of studies have investigated the relationships between inter-individual variability in brain regions’ connectivity and behavioral phenotypes, making use of large population neuroimaging datasets.
Jianxiao Wu   +6 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An analysis of metadata reporting in freshwater environmental DNA research calls for the development of best practice guidelines

open access: yesEnvironmental DNA, 2020
As environmental DNA (eDNA) becomes more widely used in research, it becomes increasingly important to have a standard set of reporting guidelines for metadata.
Andrew Nicholson   +9 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

ASA President’s Task Force Statement on Statistical Significance and Replicability

open access: yesHarvard data science review, 2021
The value of hypothesis testing, and the frequent misinterpretation of p-values as a cornerstone of statistical methodology, continues to be debated. In 2019, the President of the American Statistical Association (ASA) convened a Task Force to write a ...
Y. Benjamini   +14 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Promoting Reproducibility and Replicability in Political Science

open access: yesResearch & Politics
This article reviews and summarizes current reproduction and replication practices in political science. We first provide definitions for reproducibility and replicability.
Abel Brodeur   +14 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Replicability is not Reproducibility:\ud Nor is it Good Science [PDF]

open access: yes, 2009
At various machine learning conferences, at various times, there have been discussions arising from the inability to replicate the experimental results published in a paper.
Drummond, Dr. Chris
core   +1 more source

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