Results 81 to 90 of about 1,173,714 (339)

The completeness of intervention descriptions in published National Institute of Health Research HTA-funded trials: a cross-sectional study [PDF]

open access: yes, 2014
ObjectivesThe objective of this study was to assess whether National Institute of Health Research (NIHR) Health Technology Assessment (HTA)-funded randomised controlled trials (RCTs) published in the HTA journal were described in sufficient detail to ...
Anstee, Sydney   +5 more
core   +1 more source

Replication challenges [PDF]

open access: yesScience, 2019
The ability to test validity by replicating experiments and comparing results is a cornerstone of science. The events that followed publication of “Sustained virologic control in SIV + macaques after antiretroviral and α 4 β 7 antibody therapy” by Byrareddy
openaire   +2 more sources

#EEGManyLabs: Investigating the replicability of influential EEG experiments.

open access: yesCortex; a journal devoted to the study of the nervous system and behavior, 2020
There is growing awareness across the neuroscience community that the replicability of findings about the relationship between brain activity and cognitive phenomena can be improved by conducting studies with high statistical power that adhere to well ...
Y. Pavlov   +58 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sustainability and Replicability of Multiple-Use Water Systems (MUS) [PDF]

open access: yes, 2015
The concept of multiple-use water services and systems (MUS) has received increasingattention in international water and development fora and has emerged as a promising wayto enhance the social and gender equity and productivity of water systems designed
Floriane Clement   +2 more
core  

Replicability and generalizability in population psychiatric neuroimaging

open access: yesNeuropsychopharmacology
Studies linking mental health with brain function in cross-sectional population-based association studies have historically relied on small, underpowered samples.
Scott A. Marek, Timothy O. Laumann
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Replacing academic journals

open access: yesRoyal Society Open Science, 2023
Replacing traditional journals with a more modern solution is not a new idea. Here, we propose ways to overcome the social dilemma underlying the decades of inaction.
Björn Brembs   +9 more
doaj   +1 more source

Replicating nucleosomes [PDF]

open access: yesScience Advances, 2015
Reestablishment of the nucleosome landscape behind the replication fork is fundamental for epigenetic memory during development.
Ramachandran, Srinivas, Henikoff, Steven
openaire   +2 more sources

Replicability and Generalizability of Posttraumatic Stress Disorder (PTSD) Networks: A Cross-Cultural Multisite Study of PTSD Symptoms in Four Trauma Patient Samples

open access: yesClinical psychological science : a journal of the Association for Psychological Science, 2018
The growing literature conceptualizing mental disorders like posttraumatic stress disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise estimation, (b)
Eiko I. Fried   +9 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy