Results 31 to 40 of about 108,626 (229)
Promoting Consumer Choice and Innovative Financing Models: Lessons Learned From 25 Years of Supporting Long-Term Care [PDF]
, 2007 Provides an overview of the foundation's efforts to explore new approaches to long-term care and develop and models for reform.
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Journal of Experimental Psychopathology, 2019 Understanding attentional biases associated with body dissatisfaction can aid in devising and refining programs to reduce body dissatisfaction. This study compared attention to images of women’s bodies before and after a body satisfaction or body ...
Samantha Withnell +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Construction Theory, Self-Replication, and the Halting Problem [PDF]
, 2007 This essay aims to propose construction theory, a new domain of theoretical research on machine construction, and use it to shed light on a fundamental relationship between living and computational systems. Specifically, we argue that self-replication of
Sayama, Hiroki
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Harlem Children's Zone, Promise Neighborhoods, and the Broader, Bolder Approach to Education [PDF]
, 2010 Examines the role of community services in raising academic achievement in the Harlem Children's Zone. Questions the effectiveness of replicating the neighborhood approach, rather than the schools-only approach, in the Promise Neighborhoods ...
Grover J. Whitehurst, Michelle Croft
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Replicating Programs in Social Markets [PDF]
, 1998 This paper details the multiple factors that must be taken into account in assessing a programs chances of being successfully replicated, and investigates the various dimensions of replicability -- the program, the process, and the market. The dimensions
David Racine
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Implementation Science Communications, 2023 Background Knee osteoarthritis (OA) is a leading cause of chronic pain and disability and one of the most common conditions treated in outpatient physical therapy (PT).
Sara Webb +17 more
doaj +1 more source