Results 51 to 60 of about 7,284,411 (284)

Implementing evidence-based interventions in health care: application of the replicating effective programs framework-0

open access: yes, 2011
Copyright information:Taken from "Implementing evidence-based interventions in health care: application of the replicating effective programs framework"http://www.implementationscience.com/content/2/1/42Implementation science : IS 2007;2():42-42 ...
Mark S Bauer (87380)   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Group physical therapy for knee osteoarthritis: protocol for a hybrid type III effectiveness-implementation trial

open access: yesImplementation Science Communications, 2023
Background Knee osteoarthritis (OA) is a leading cause of chronic pain and disability and one of the most common conditions treated in outpatient physical therapy (PT).
Sara Webb   +17 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Chronic Hepatitis B in Canada

open access: yesCanadian Journal of Infectious Diseases, 2001
Recent developments in the treatment and prevention of hepatitis B virus (HBV) infections warrant revisiting important epidemiological questions, such as how prevalent is chronic HBV infection in Canada, in which Canadian subpopulations are HBV ...
GY Minuk, J Uhanova
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

TRIO Programs: TRIO Day Magazine [PDF]

open access: yes, 2010
Magazine for TRIO Day 2010 -- Disability Support Services -- Office of Disability Services -- Talent Search -- Ronald E. McNair Post-Baccalaureate Achievement Program -- Upward Bound Math/Science Regional Center -- Upward Bound Wichita Prep -- Veterans ...
Office of Special Programs
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Factors contributing to intervention fidelity in a multi-site chronic disease self-management program

open access: yesImplementation Science, 2006
Background and objectives Disease self-management programs have been a popular approach to reducing morbidity and mortality from chronic disease. Replicating an evidence-based disease management program successfully requires practitioners to ensure ...
Pitt Seraphine   +7 more
doaj   +1 more source

Mycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosis. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: New diagnosis tests are urgently needed to address the global tuberculosis (TB) burden and to improve control programs especially in resource-limited settings.
Belinda Brust   +6 more
doaj   +1 more source

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