Results 41 to 50 of about 109,369 (285)
Promoting Consumer Choice and Innovative Financing Models: Lessons Learned From 25 Years of Supporting Long-Term Care [PDF]
Provides an overview of the foundation's efforts to explore new approaches to long-term care and develop and models for reform.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Taking Care of the New Home Front: Leveraging Greater Federal Resources to Expand Community Capacity for NYS Veterans and Families [PDF]
This report from the Syracuse University Institute for Veterans and Military Families (IVMF) looks at the progress of the Supportive Services for Veteran Families (SSVF) program, a first-of-its-kind initiative that assists veteran families at imminent ...
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Background Knee osteoarthritis (OA) is a leading cause of chronic pain and disability and one of the most common conditions treated in outpatient physical therapy (PT).
Sara Webb +17 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Intellectual Property Challenges in Replicating an American Graduate Program in Poland Experiences, Perspectives, and Lessons Learned [PDF]
The article delineates some of the challenges in implementing of one of the global trends among universities - increased cooperation and collaboration to create and transfer intellectual property.
Gwarda Gruszczyńska, Edyta +2 more
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Recent developments in the treatment and prevention of hepatitis B virus (HBV) infections warrant revisiting important epidemiological questions, such as how prevalent is chronic HBV infection in Canada, in which Canadian subpopulations are HBV ...
GY Minuk, J Uhanova
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Harlem Children's Zone, Promise Neighborhoods, and the Broader, Bolder Approach to Education [PDF]
Examines the role of community services in raising academic achievement in the Harlem Children's Zone. Questions the effectiveness of replicating the neighborhood approach, rather than the schools-only approach, in the Promise Neighborhoods ...
Grover J. Whitehurst, Michelle Croft
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