Results 151 to 160 of about 1,779,695 (298)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Literature review on provision of appropriate and accessible support to people with an intellectual disability who are experiencing crisis pregnancy

open access: yes, 2011
The Crisis Pregnancy Agency [2] and the National Disability Authority commissioned this systematic review of Irish and international literature to identify international models of good practice regarding crisis pregnancy counselling and support ...
O'Connor, Joan
core  

Psychological effects of abortion on women: a review of the literature [PDF]

open access: yes, 2007
The psychological effects of abortion have been the subject of scientific investigation, as well as public debate internationally, for several decades and have generated a great deal of discussion, as well as some controversy.
Fine-Davis, Margaret
core  

What the replication crisis means for intervention science. [PDF]

open access: yesInt J Psychophysiol, 2020
Hillary FG, Medaglia JD.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Crisis pregnancy counselling in Ireland

open access: yes, 2004
Between September 2002 and September 2003 Dr. Saoirse Nic Gabhainn and Dr. Vivienne Batt of the Centre for Health Promotion Studies and the Women’s Studies Centre, National University of Ireland, Galway conducted research on behalf of the Crisis ...
Nic Gabhainn, Saoirse, Batt, Vivienne
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Understanding how sexually active women think about fertility, sex, and motherhood [PDF]

open access: yes, 2004
The subject of this report is the perceptions of Irish women in the general age range of 20-30 about fertility, sex, and motherhood. The report captures the meanings young women attribute to their fertility and fertility-related decisions in relation ...
Brady, Clare   +2 more
core  

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