Results 131 to 140 of about 1,779,695 (298)
Healing the trauma of rape and sexual abuse (second report)
, 1995 Since the last RCC report was published the nation has been made tragically aware of sexual violence in our community, particularly as it affects defenceless children.
Rape Crisis Centre.
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Towards a strategy to address the issue of crisis pregnancy
, 2003 The Crisis Pregnancy Agency was established in October 2001, under the Health (Corporate Bodies) Act, 1961, and governed by the Statutory Instrument No. 446 of 2001, Crisis Pregnancy Agency, Establishment Order, 2001.
Crisis Pregnancy Agency
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Do we focus on process over outcome? Review of published studies in two prominent saudi journals
Cogent EducationIt is well-known that published science is judged by the judicious and careful use of methods employed when acquiring knowledge and understanding. However, since the beginning of the millennia, concerns over the validity and reliability of scientific ...
Ruwayshid Alruwaili
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Strategy 2007 - 2011: Leading an integrated approach to reducing crisis pregnancy
, 2007 The Strategy for the Crisis Pregnancy Agency 2007 – 2011 focuses on three central objectives, derived from its mandates: • Reduce the number of crisis pregnancies.
Crisis Pregnancy Agency
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Statistical reform and the replication crisis
, 2018 The replication crisis has prompted many to call for statistical reform within the psychological sciences. Here we examine issues within Frequentist statistics that may have led to the replication crisis, and we examine the alternative---Bayesian statistics---that many have suggested as a replacement.
Colling, Lincoln J, Szucs, Denes
openaire +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Editorial: Evidential Statistics, Model Identification, and Science
Frontiers in Ecology and Evolution, 2022 Mark L. Taper +3 more
doaj +1 more source