Results 101 to 110 of about 76,259 (304)
Interfacial instability and DNA fork reversal by repair proteins [PDF]
, 2009 A repair protein like RecG moves the stalled replication fork in the direction from the zipped to the unzipped state of DNA. It is proposed here that a softening of the zipped-unzipped interface at the fork results in the front propagating towards the ...
Bhattacharjee, Somendra M.
core +2 more sources
Replication forks, chromatin loops and dormant replication origins [PDF]
Genome Biology, 2008 When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.
Blow, J. Julian, Ge, Xin Q
openaire +3 more sources
Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov +2 more
wiley +1 more source
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network [PDF]
, 2012 During DNA replication, stalled replication forks and DSBs arise when the replication fork encounters ICLs (interstrand crosslinks), covalent protein/DNA intermediates or other discontinuities in the template.
Campbell, Judith L +4 more
core +3 more sources
Advanced Engineering Materials, EarlyView.The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin +2 more
wiley +1 more source
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
Nature Communications, 2019 Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.
Eva Malacaria +7 more
doaj +1 more source
The DNA damage checkpoint response to replication stress: A Game of Forks.
Frontiers in Genetics, 2013 Conditions challenging replication fork progression, collectively referred to as replication stress, represent a major source of genomic instability and are associated to cancer onset.
Rachel eJossen, Rodrigo eBermejo
doaj +1 more source
Advanced Engineering Materials, EarlyView.Identified through the use of statistical design of experiments and metallographic investigation, this study exposes the stochastic origins of intergranular cracks in blown powder laser beam directed energy deposition additive manufacturing of pure molybdenum. It further demonstrates a successful crack mitigation approach with direct correlation to the
Nathaniel J. Lies +2 more
wiley +1 more source
Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA [PDF]
, 2012 The checkpoint kinases Chk1 and ATR are broadly known for their role in the response to the accumulation of damaged DNA. Because Chk1 activation requires its phosphorylation by ATR, it is expected that ATR or Chk1 down-regulation should cause similar ...
Federico, Maria Belén +4 more
core +1 more source
Advanced Engineering Materials, Volume 28, Issue 11, 3 June 2026.Viktoriia Shtefan, Thorgund Nemec, Ute Hempel, Annett Gebert and coworkers demonstrate that anodic treatment of Ti–Cu‐based metallic glass in a nontoxic pyrophosphate electrolyte forms a protective bilayered Ti/Zr‐oxide film enriched with Cu nanocrystals.
Viktoriia Shtefan +8 more
wiley +1 more source