Results 111 to 120 of about 247,162 (311)

The dynamics of genome replication using deep sequencing [PDF]

, 2014
Peer ...
Blythe, Martin J., Nieduszynski, Conrad A, de Moura, Alessandro P. S., Nakato, Ryuichiro, Shirahige, Katsuhiko, de Moura, Alessandro P S, Malla, Sunir, Nieduszynski, Conrad A., Hawkins, Michelle, Müller, Carolin A, M�ller, Carolin A., Müller, Carolin A., de Moura, Alessandro P.S., Retkute, Renata, Wilson, Ray, Komata, Makiko, Blythe, Martin J   +16 more
core   +1 more source

The DNA replication initiation protein DnaD recognises a specific strand of the Bacillus subtilis chromosome origin

, 2023
Genome replication is a fundamental biological activity shared by all organisms. Chromosomal replication proceeds bidirectionally from origins, requiring the loading of two helicases, one for each replisome. However, the molecular mechanisms underpinning
Tiago R D Costa, Nora B Cronin, Winterhalter, Charles, Marchand, E, Murray, H, Fenyk, S, Elie Marchand, Soultanas, P, Aravindan Ilangovan, Soultanas, Panos, Ilangovan, A, Daniel Stevens, Heath Murray, Panos Soultanas, Costa, TRD, Fenyk, Stepan, Costa, Tiago R.D., Cronin, Nora B, Winterhalter, C, Stevens, Daniel, Cronin, NB, Ilangovan, Aravindan, Costa, Tiago R D, Murray, Heath, Pelliciari, S, Stepan Fenyk, Simone Pelliciari, Charles Winterhalter, Pelliciari, Simone, Costa, Tiago RD, Stevens, D, Marchand, Elie   +31 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]

, 2011
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nejman, Bożena, Nadratowska-Wesołowska, Beata, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Szalewska-Pałasz, Agnieszka   +4 more
core  

Decreased MCM2-6 in Drosophila S2 cells does not generate significant DNA damage or cause a marked increase in sensitivity to replication interference.

, 2011
A reduction in the level of some MCM proteins in human cancer cells (MCM5 in U20S cells or MCM3 in Hela cells) causes a rapid increase in the level of DNA damage under normal conditions of cell proliferation and a loss of viability when the cells are ...
Cotterill, S., Vincent Coulon, Christelle de Renty, Gostan, T., Isabelle Crevel, Renty, C., De, Gostan, T, Cotterill, S, Renty, C.,, Crevel Isabelle, Gostan Thierry, Crevel, G., Crevel, I., Cotterill Sue, Crevel Gilles, Coulon Vincent, de Renty, C, Crevel, G, Crevel, I, Gilles Crevel, Coulon, V., Thierry Gostan, de Renty Christelle, Sue Cotterill, Coulon, V   +24 more
core   +1 more source

Eukaryotic DNA replication with purified budding yeast proteins

, 2021
The in vitro reconstitution of origin firing was a key step toward the biochemical reconstitution of eukaryotic DNA replication in budding yeast. Today the basic replication assay involves proteins purified from 24 separate protocols that have evolved ...
Erik Johansson, Diffley, J. F. X., Johansson, Erik,, Johansson, E., John F.X. Diffley, Posse, Viktor,, Viktor Posse, Diffley, John F. X.,   +7 more
core   +1 more source

origin of replication

, 2014
Citation: 'origin of replication' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.O04330 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Plastid Division: The Origin of Replication [PDF]

The Plant Cell, 1998
The fact that chlorophyll-containing chloroplasts are remarkably abundant organelles in plants is obvious to anyone contemplating the verdant green expanses of most global ecosystems. For those who have viewed leaf mesophyll cells by peering down a microscope, it is also apparent that ...
openaire   +2 more sources

Separating the effects of mutation and selection in producing DNA skew in bacterial chromosomes

BMC Genomics, 2007
Background Many bacterial chromosomes display nucleotide asymmetry, or skew, between the leading and lagging strands of replication. Mutational differences between these strands result in an overall pattern of skew that is centered about the origin of ...
Morton Brian R, Morton Richard A
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source