Results 191 to 200 of about 3,588,418 (239)
Some of the next articles are maybe not open access.
DNA replication origin activation in space and time
Nature Reviews Molecular Cell Biology, 2015M. Fragkos +3 more
semanticscholar +3 more sources
Replication origins in eukaroytes
Current Opinion in Genetics & Development, 1996Recent experiments in budding yeast and Xenopus have provided new insights into the regulation of eukaroytic DNA replication. The multi-subunit origin recognition complex plays a key role in initiation, remaining bound at origins of replication during most of the cell cycle.
S, Donovan, J F, Diffley
openaire +2 more sources
Unearthing worm replication origins
Nature Structural & Molecular Biology, 2017Unlike in animals in which gastrulation marks the onset of zygotic transcription and a transition from random to site-specific localization of replication origins, transcription and origin specification in Caenorhabditis elegans are in place before gastrulation.
Takayo, Sasaki, David M, Gilbert
openaire +2 more sources
Mammalian origins of replication
BioEssays, 1992AbstractIt has been almost twenty‐five years since Huberman and Riggs first showed that there are multiple bidirectional origins of replication scattered at ∼100 kb intervals along mammalian chromosomal fibers. Since that time, every conceivable physical property unique to replicating DNA has been taken advantage of to determine whether origins of ...
openaire +2 more sources
Cybernetic origins of replication
Origins of life and evolution of the biosphere, 1988An evolutionary progression leading toward replication is resolved into several phases; (a) the replication of RNA segments by self-priming and -templating, (b) the replication of single stranded molecules by elongation and controlled scission, (c) replication of complementary duplexes and (d) replication of DNA.
openaire +2 more sources
Bacterial chromosome origins of replication
Current Opinion in Genetics & Development, 1993Bacteria regulate chromosomal replication from one specific origin. We compare the regulatory requirements, DNA structures, and biochemical properties of the prototypic Escherichia coli origin with those of evolutionarily distant Bacillus subtilis and Caulobacter crescentus origins.
G T, Marczynski, L, Shapiro
openaire +2 more sources
Eucaryotic replication origin binding proteins
Frontiers in Bioscience, 2004Initiation of eukaryotic DNA replication is a tightly controlled process. Replication initiates at multiple specific sites (replication origins) that have been licensed for replication, following the cell cycle-dependent, multi-step assembly of specific factors.
Maria, Zannis-Hadjopoulos +2 more
openaire +2 more sources
Two replication initiators – one mechanism for replication origin opening?
Plasmid, 2014DNA replication initiation has been well-characterized; however, studies in the past few years have shown that there are still important discoveries to be made. Recent publications concerning the bacterial DnaA protein have revealed how this replication initiator, via interaction with specific sequences within the origin region, causes local ...
Elzbieta, Zabrocka +2 more
openaire +2 more sources
Cancer: Involvement of replicative origins?
Medical Hypotheses, 1986The assumption is made that movable genetic elements related to cancer are replicons and/or replicative origins. Some evidence is provided that certain mobile Alu-origins may represent candidates for precursors of chromosomal insertions. They could incorporate and interact with "fixed" chromosomal origins converting them to "procaryotic" ones. In other
openaire +2 more sources