Results 181 to 190 of about 1,154,263 (301)

Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation. [PDF]

Chembiochem, 2023
Greenwood SN, Kulkarni RS, Mikhail M, Weiser BP.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Characterization of antibodies against the replication protein (Rep) encoded by bovine meat and milk factors (BMMFs). [PDF]

Appl Microbiol Biotechnol
Frehtman V, Shukla G, Gentz M, Müller M, Duduyemi OP, Grewe I, Ernst C, Tessmer C, Didier A, Hofmann I, Bund T, Leuchs B.   +11 more
europepmc   +1 more source

The DNA replication protein Orc1 from the yeast Torulaspora delbrueckii is required for heterochromatin formation but not as a silencer-binding protein. [PDF]

Genetics, 2022
Maria H, Rusche LN.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Clinicopathological and functional evaluation of replication protein A in epithelial ovarian cancers: A target validation study. [PDF]

Transl Oncol
Algethami M, Sheha A, Singhania N, Alqahtani S, Shoqafi A, Tosun Ç, Spicer J, Toss MS, Alblihy A, Lashen A, Jeyapalan JN, Mongan NP, Rakha EA, Madhusudan S.   +13 more
europepmc   +1 more source

Correction: DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival. [PDF]

PLoS Pathog, 2023
Yadav A, Sharma V, Pal J, Gulati P, Goel M, Chandra U, Bansal N, Saha S.   +7 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors. [PDF]

Nucleic Acids Res
VanderVere-Carozza PS, Jordan MR, Garrett JE, Pollok KE, Pawelczak KS, Turchi JJ.   +5 more
europepmc   +1 more source

Replication Protein A Utilizes Differential Engagement of Its DNA-Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes. [PDF]

Biochemistry, 2022
Wieser TA, Wuttke DS.
europepmc   +1 more source