Results 211 to 220 of about 817,676 (313)

Structural and functional studies of the main replication protein NS1 of human parvovirus B19. [PDF]

Nucleic Acids Res
Zhang Y, Fan B, Gao Y, Yang J, Zhang W, Su S, Li L, Li H, Luo Z, Tang G, Wang C, Zhang X, Liu H, Gan J.   +13 more
europepmc   +1 more source

Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells. [PDF]

Mol Cell Biol, 2022
Carley AC, Jalan M, Subramanyam S, Roy R, Borgstahl GEO, Powell SN.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Efficient activity of uracil DNA glycosylase (UNG2) in proliferating cells requires binding to proliferating cell nuclear antigen (PCNA) and replication protein A (RPA). [PDF]

DNA Repair (Amst)
Kulkarni RS, Weiser BP.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Investigation of truncated replication protein mutant of Canine Circovirus: synergistic interaction with Feline Panleukopenia Virus. [PDF]

Front Vet Sci
Li S, Xin J, Peng Y, Liu H, Zhou Z, Zhong Z, Fu H, Yang M, Li W, Wu R, Peng G.   +10 more
europepmc   +1 more source

Hydrogen-deuterium exchange reveals a dynamic DNA-binding map of replication protein A. [PDF]

Nucleic Acids Res, 2021
Ahmad F, Patterson A, Deveryshetty J, Mattice JR, Pokhrel N, Bothner B, Antony E.   +6 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Human hnRNPA1 reorganizes telomere-bound replication protein A. [PDF]

Nucleic Acids Res
Granger SL, Sharma R, Kaushik V, Razzaghi M, Honda M, Gaur P, Bhat DS, Labenz SM, Heinen JE, Williams BA, Tabei SMA, Wlodarski MW, Antony E, Spies M.   +13 more
europepmc   +1 more source

A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability. [PDF]

Nat Commun, 2021
Wang L, Li J, Zhou H, Zhang W, Gao J, Zheng P.   +5 more
europepmc   +1 more source