Results 11 to 20 of about 2,724,889 (347)

Inferential Statistics as Descriptive Statistics: There Is No Replication Crisis if We Don’t Expect Replication [PDF]

open access: bronzeAmerican Statistician, 2019
Statistical inference often fails to replicate. One reason is that many results may be selected for drawing inference because some threshold of a statistic like the P-value was crossed, leading to biased reported effect sizes.
Valentin Amrhein   +2 more
openalex   +2 more sources

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.

open access: yesPLoS Genetics, 2016
Most of the genetic architecture of schizophrenia (SCZ) has not yet been identified. Here, we apply a novel statistical algorithm called Covariate-Modulated Mixture Modeling (CM3), which incorporates auxiliary information (heterozygosity, total linkage ...
Yunpeng Wang   +23 more
doaj   +2 more sources

Statistical methods for replicability assessment [PDF]

open access: yesThe Annals of Applied Statistics, 2020
Large-scale replication studies like the Reproducibility Project: Psychology (RP:P) provide invaluable systematic data on scientific replicability, but most analyses and interpretations of the data fail to agree on the definition of "replicability" and disentangle the inexorable consequences of known selection bias from competing explanations.
Hung, Kenneth, Fithian, William
openaire   +3 more sources

Publications, replication and statistics in physiology plus two neglected curves

open access: yesJournal of Physiology, 2021
I was asked to write a short editorial to reflect on my links to The Journal of Physiology and to consider some of the changes in physiology reflected in The Journal.
S. Gandevia
semanticscholar   +1 more source

The new normal? Redaction bias in biomedical science

open access: yesRoyal Society Open Science, 2021
A concerning amount of biomedical research is not reproducible. Unreliable results impede empirical progress in medical science, ultimately putting patients at risk.
David Robert Grimes, James Heathers
doaj   +1 more source

LZS bioactive glass-ceramic scaffolds: Colloidal processing, foam replication technique and mechanical properties to bone tissue engineering

open access: yesOpen Ceramics, 2022
Scaffolds are used in bone replacement because present biocompatibility, three-dimensional structure, and high porosity. However, despite the efforts, there are still significant barriers to the development of reliable, synthetic scaffolds to repair ...
Natália Morelli Possolli   +3 more
doaj   +1 more source

Probabilistic model based on circular statistics for quantifying coverage depth dynamics originating from DNA replication [PDF]

open access: yesPeerJ, 2020
Background With the development of DNA sequencing technology, static omics profiling in microbial communities, such as taxonomic and functional gene composition determination, has become possible.
Shinya Suzuki, Takuji Yamada
doaj   +2 more sources

A Semi-Static Replication Method for Bermudan Swaptions under an Affine Multi-Factor Model

open access: yesRisks, 2023
We present a semi-static replication algorithm for Bermudan swaptions under an affine, multi-factor term structure model. In contrast to dynamic replication, which needs to be continuously updated as the market moves, a semi-static replication needs to ...
Jori Hoencamp   +2 more
doaj   +1 more source

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