Results 201 to 210 of about 2,618,656 (372)

Death by statistics — When one replicate is enough

open access: yes
This week, I committed statistical blasphemy by arguing that, in some cases, one replicate can be enough for a specific type of molecular biology experiment. Before you rush to conclusions, let me explain. I haven’t lost my mind. A single experiment would prove me wrong What I like about this quote To be less and less wrong How many replicates is ...
openaire   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Phylogenetic signatures reveal multilevel selection and fitness costs in SARS-CoV-2 [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research
Background Large-scale sequencing of SARS-CoV-2 has enabled the study of viral evolution during the COVID-19 pandemic. Some viral mutations may be advantageous to viral replication within hosts but detrimental to transmission, thus carrying a transient ...
Erik Volz, Vinicius Bonetti Franceschi
doaj  

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

open access: yesAdvanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers   +3 more
wiley   +1 more source

USP37 prevents premature disassembly of stressed replisomes by TRAIP. [PDF]

open access: yesNat Commun
Kochenova OV   +15 more
europepmc   +1 more source

Replication is more than hitting the lottery twice [PDF]

open access: yes, 2013
Asendorpf, Jens B   +15 more
core   +1 more source

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