Results 241 to 250 of about 2,724,889 (347)

Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health. [PDF]

Nat Aging
Jawinski P, Forstbach H, Kirsten H, Beyer F, Villringer A, Witte AV, Scholz M, Ripke S, Markett S.   +8 more
europepmc   +1 more source

Cost‐Effectiveness of Low‐Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start‐Low Go‐Slow” Approach for Gout: Evidence From a Noninferiority Randomized Double‐Blind Placebo‐Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko, Ross Wilson, Nicola Dalbeth, J. Haxby Abbott, Lisa Stamp   +4 more
wiley   +1 more source

Alternative polyadenylation upon CPSF6 knock-out enhances HIV-1 infection in primary T cells. [PDF]

PLoS Pathog
Cornish D, Jackson-Jones KA, Ling-Hu T, Simons LM, Cisneros WJ, Kuffour EO, Stegman N, Agnes F, Lee Y, Sharma VP, Bieniasz PD, Lorenzo-Redondo R, Hultquist JF.   +12 more
europepmc   +1 more source

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher, Sam Norton, Joseph L. Taylor, Bina Menon, Tom Esterine, Ruth Williams, Leonie S. Taams, Kirsty Bannister, Bruce W. Kirkham   +8 more
wiley   +1 more source

Serum Biochemical Markers and Rheumatoid Arthritis: Insights From Observational Study and Mendelian Randomization Analysis. [PDF]

Int J Rheum Dis
Fan F, Tan H, Xie Y, Qin H, Zhang C, Wang H, Yan W, Zhou A, Lei L, Lian C.   +9 more
europepmc   +1 more source

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

Arthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Identification of potential bladder cancer drug targets through Mendelian randomization and molecular docking. [PDF]

Discov Oncol
Bi C, Li K, Yang Y, Shi Y, Zhang G, Zhao B, Duan Y, Xing Y, Luo W, Yang L, Zhang Y, Huang Y.   +11 more
europepmc   +1 more source

Replication data for: Idaho Parks, Recreation and Travel Statistics 1975-1991 (26 Tables)

, 2012
Unav
openalex   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases. [PDF]

Cell Death Dis
Okraine YV, de la Vega MB, Venerus Arbilla S, Moyano G, Bertolin AP, Pallarés HM, Wiesmüller L, Mansilla SF, Gottifredi V.   +8 more
europepmc   +1 more source