Results 51 to 60 of about 2,724,889 (347)

Replication in Genome-Wide Association Studies

, 2010
Replication helps ensure that a genotype-phenotype association observed in a genome-wide association (GWA) study represents a credible association and is not a chance finding or an artifact due to uncontrolled biases.
Ioannidis, John P. A., Kraft, Peter, Zeggini, Eleftheria   +2 more
core   +1 more source

Abandon Statistical Significance [PDF]

, 2018
We discuss problems the null hypothesis significance testing (NHST) paradigm poses for replication and more broadly in the biomedical and social sciences as well as how these problems remain unresolved by proposals involving modified p-value thresholds ...
Gal, David, Gelman, Andrew, McShane, Blakeley B., Robert, Christian, Tackett, Jennifer L.   +4 more
core   +2 more sources

A multivariate empirical Bayes statistic for replicated microarray time course data

, 2007
In this paper we derive one- and two-sample multivariate empirical Bayes statistics (the $\mathit{MB}$-statistics) to rank genes in order of interest from longitudinal replicated developmental microarray time course experiments.
Speed, Terence P., Tai, Yu Chuan
core   +1 more source

Replication assessment of NUS1 variants in Parkinson's disease

Neurobiology of Aging, 2020
The NUS1 gene was recently associated with Parkinson's disease (PD) in the Chinese population. Here, as part of the International Parkinson's Disease Genomics Consortium (IPDGC), we have leveraged large-scale PD case-control cohorts to comprehensively ...
B. Bustos, S. Bandres-Ciga, J. Gibbs, D. Krainc, N. Mencacci, Z. Gan-Or, S. Lubbe   +6 more
semanticscholar   +1 more source

Statistical Literacy Among Applied Linguists and Second Language Acquisition Researchers

, 2014
The importance of statistical knowledge in applied linguistics and second language acquisition (SLA) research has been emphasized in recent publications.
Aiken, Aiken, Aiken, Alder, Bailey, Barkhuizen, Beyth-Marom, Brown, Brown, Brown, Chapelle, Cumming, Cunnings, Curtis, Ellis, Ellis, Fidler, Field, Finney, Gass, Henson, Larson-Hall, Larson-Hall, Lazaraton, Lazaraton, Lazaraton, Leech, Loewen, Norris, Plonsky, Plonsky, Porte, Richards, Zimiles   +33 more
core   +1 more source

Bifurcation into functional niches in adaptation [PDF]

, 2004
One of the central questions in evolutionary biology concerns the dynamics of adaptation and diversification. This issue can be addressed experimentally if replicate populations adapting to identical environments Call be investigated in detail.
Adami, Christoph, White, Justin S.
core   +2 more sources

Kontrola tačnosti rezultata u simulacijama Monte Karlo / Accuracy control in Monte Carlo simulations

Vojnotehnički Glasnik, 2010
U radu je demonstrirana primena metode automatizovanog ponavljanja nezavisnih simulacionih eksperimenata sa prikupljanjem statistike slučajnih procesa, u dostizanju i kontroli tačnosti simulacionih rezultata u simulaciji sistema masovnog opsluživanja ...
Nebojša V. Nikolić
doaj   +1 more source

Reproducible Econometric Research. A Critical Review of the State of the Art. [PDF]

, 2007
Recent software developments are reviewed from the vantage point of reproducible econometric research. We argue that the emergence of new tools, particularly in the open-source community, have greatly eased the burden of documenting and archiving both ...
Koenker, Roger, Zeileis, Achim
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Statistics as a Social Activity: Attitudes toward Amalgamating Evidence

Entropy
Amalgamation of evidence in statistics is conducted in several ways. Within a study, multiple observations are combined by averaging, or as factors in a likelihood or prediction algorithm.
Andrew Gelman, Keith O’Rourke
doaj   +1 more source