Results 81 to 90 of about 6,315 (345)

Replicator Dynamics with Frequency Dependent Stage Games [PDF]

open access: yes
We analyze evolutionary games with replicator dynamics that have frequency dependent stage games. In such an evolutionary game, the payoffs of a strategy at any point in time are functions of the strategy shares given by the players' strategy choices at ...
Esther Bruegger
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On evolutionarily stable strategies and replicator dynamics in asymmetric two-population games [PDF]

open access: yes
We analyze the main dynamical properties of the evolutionarily stable strategy ESS for asymmetric two-population games of finite size in its corresponding replicator dynamics.
Elvio Accinelli   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Hybrid Model-Based Traffic Network Control Using Population Games

open access: yesApplied System Innovation
Modern traffic management requires sophisticated approaches to address the complexities of urban road networks, which continue to grow in complexity due to increasing urbanization and vehicle usage.
Sindy Paola Amaya   +4 more
doaj   +1 more source

Evolutionary dynamics may eliminate all strategies used in correlated equilibrium [PDF]

open access: yes
In (Viossat, 2006, "The replicator dynamics does not lead to correlated equilibria", forthcoming in Games and Economic Behavior), it was shown that the replicator dynamics may eliminate all pure strategies used in correlated equilibrium, so that only ...
Viossat, Yannick
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Evolutionary Stability of First Price Auctions [PDF]

open access: yes
This paper studies the evolutionary stability of the unique Nash equilibrium of a first price sealed bid auction. It is shown that the Nash equilibrium is not asymptotically stable under payoff monotonic dynamics for arbitrary initial popu- lations.
Frank Riedel, Fernando Louge
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Replication in DHTs Using Dynamic Groups [PDF]

open access: yes, 2011
Distributed Hash Tables (DHTs) provide an efficient solution for data location and lookup in large-scale P2P systems. However, it is up to the applications to deal with the availability of the data they store in the DHT, e.g. via replication. To improve data availability, most DHT applications rely on data replication.
Akbarinia, Reza   +4 more
openaire   +3 more sources

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