Results 71 to 80 of about 6,315 (345)

A Robust Population Dynamics Model With Carrying Capacity Constraints for Centrally Coordinated Distributed Optimization

open access: yesIEEE Access
Distributed optimization is crucial for managing complex, large-scale systems, yet faces challenges in achieving robustness and efficiency under practical constraints.
German Obando, Andres Pantoja
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Shapley Polygons in 4 x 4 Games

open access: yesGames, 2010
We study 4 x 4 games for which the best response dynamics contain a cycle. We give examples in which multiple Shapley polygons occur for these kinds of games.
Martin Hahn
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Replicator dynamics.

open access: yes, 2019
The set of points determined by values of ϕ and q, illustrating the basin of attraction and typical trajectories of the replicator dynamics, with an unstable rest point where ϕ = q = 0 and stable rest point and global attractor at ϕ = q = 1.
Edmund Chattoe-Brown (6616316)   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Time Average Replicator and Best Reply Dynamics [PDF]

open access: yes
Using an explicit representation in terms of the logit map we show, in a unilateral framework, that the time average of the replicator dynamics is a perturbed solution of the best reply dynamics.replicator dynamics; best reply dynamics; logit map ...
Yannick Viossat   +2 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Selection-Mutation Dynamics of Signaling Games

open access: yesGames, 2015
We study the structure of the rest points of signaling games and their dynamic behavior under selection-mutation dynamics by taking the case of three signals as our canonical example. Many rest points of the replicator dynamics of signaling games are not
Josef Hofbauer, Simon M. Huttegger
doaj   +1 more source

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