Results 61 to 70 of about 2,501 (260)

Biogenesis and Dynamics of the Coronavirus Replicative Structures [PDF]

open access: yesViruses, 2012
Coronaviruses are positive-strand RNA viruses that are important infectious agents of both animals and humans. A common feature among positive-strand RNA viruses is their assembly of replication-transcription complexes in association with cytoplasmic membranes.
Hagemeijer, M.C.   +2 more
openaire   +5 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Improving replicator dynamic evolutionary game model for selecting optimal defense strategies

open access: yesTongxin xuebao, 2018
In terms of the existence of strategy dependency in the same game group,network attack-defense evolutionary game model based on the improved replicator dynamics was constricted by introducing the intensity coefficient,which completed the method of ...
Jianming HUANG, Hengwei ZHANG
doaj   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Decoding the behavioural dynamics of vaccination: how pre-emptive and post-recovery vaccinations shape epidemic outcomes [PDF]

open access: yesRoyal Society Open Science
This study presents a coupled behavioural–epidemiological framework that integrates an extended susceptible–infected–recovered–susceptible model with evolutionary game theory to analyse timing-based vaccination strategies, specifically pre-infection and ...
Nihal Majumder, Md. Rajib Arefin
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Group Selection Under the Replicator Dynamic

open access: yesDynamic Games and Applications, 2023
Abstract We consider a society where individuals get divided into different groups, each playing a different strict Nash equilibrium of the same game. Under group selection, a group playing a Nash equilibrium with a higher payoff evolves faster.
openaire   +1 more source

A Robust Population Dynamics Model With Carrying Capacity Constraints for Centrally Coordinated Distributed Optimization

open access: yesIEEE Access
Distributed optimization is crucial for managing complex, large-scale systems, yet faces challenges in achieving robustness and efficiency under practical constraints.
German Obando, Andres Pantoja
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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