Results 51 to 60 of about 2,501 (260)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Dynamics of Coronavirus Replication-Transcription Complexes [PDF]
Journal of Virology, 2010 ABSTRACT Coronaviruses induce in infected cells the formation of double-membrane vesicles (DMVs) in which the replication-transcription complexes (RTCs) are anchored. To study the dynamics of these coronavirus replicative structures, we generated recombinant murine hepatitis coronaviruses that express tagged versions of the nonstructural ...
Hagemeijer, Marne C +7 more
openaire +6 more sources
Tongxin xuebao, 2012 The substrate network path selection problem of virtual network was modeled as an evolutionary game.In the process of evolutionary game,virtual networks adjusted the strategies through the iterated game.The replicator dynamics were leveraged equation to ...
Yu YANG, Shan-zhi CHEN, Xin LI
doaj +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Model of DNA Dynamics and Replication [PDF]
Journal of Biological Physics, 2005 Before DNA replication can be initiated a definite number of adenosine triphosphate (ATP) containing pre-replication protein complexes (pre-RCs) must be assembled and bound to DNA like in a super-critical mass. A chemically driven dynamics of the Ginzburg-Landau (GL) type is derived, using the non-equilibrium equation for binding of pre-RCs to DNA and ...
openaire +2 more sources
Applied Sciences, 2023 In the digital era, smart-home users face growing threats from cyberattacks that threaten their privacy and security. Hence, it is essential for smart-home users to prioritize cybersecurity education and training to secure their homes.
N’guessan Yves-Roland Douha +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Replicator Dynamics of Symmetric Ultimatum Game [PDF]
Dynamic Games and Applications, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jacek Miekisz, Michal Ramsza
openaire +1 more source
How Moral Codes Evolve in a Trust Game
Games, 2015 This paper analyzes the dynamic stability of moral codes in a two population trust game. Guided by a moral code, members of one population, the Trustors, are willing to punish members of the other population, the Trustees, who defect.
Jean Paul Rabanal, Daniel Friedman
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source