Results 221 to 230 of about 105,162 (327)

Influence of steroid hormones on ventricular repolarization.

open access: yesPharmacology and Therapeutics, 2016
J. Salem   +3 more
semanticscholar   +1 more source

Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent

open access: yesExperimental Physiology, EarlyView.
Abstract Oestradiol (17β‐E2) is reported to prolong the cardiac action potential duration and QT interval, in part by affecting cardiac ion channels. Previous studies found inhibiting 17β‐E2 effects on the repolarizating cardiac KV7.1/KCNE1 channel, or its native current, in heterologous expression systems or tissue from animal species.
Veronika A. Linhart   +2 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

open access: yesExperimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene   +4 more
wiley   +1 more source

From Whole Exome Sequencing to Patient‐Specific Therapy: Another Example of How Basic Research Pays Off in Patient Care

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Arthur A. M. Wilde, Sami Viskin
doaj   +1 more source

Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes

open access: yesExperimental Physiology, EarlyView.
Abstract Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) have proven to be a revolutionary advance for tissue engineering, disease modelling, and drug testing and discovery. Computational modelling enables detailed electrophysiological analysis that is otherwise difficult or impossible to achieve under strictly experimental ...
Roshni Shetty   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy