Advancements in the application of reporter gene cell lines in bioactivity evaluation of biological products. [PDF]
Yi K, Wang C, Lu H.
europepmc +1 more source
Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. [PDF]
Li Y +11 more
europepmc +1 more source
Evaluation of a novel luciferase reporter construct: a positive control plasmid for reporter gene assay [PDF]
Tewin Tencomnao +2 more
openalex
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Three isoforms of <i>Brugia malayi</i> <i>daf-16</i> activate a reporter gene in cultured HepG2 cells. [PDF]
Zehr CE +4 more
europepmc +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Functional analysis of thiamine pyrophosphate-responsive riboswitches in human bacterial pathogens of the ESKAPE group using a dual-luciferase reporter gene assay. [PDF]
Hübenthal A +3 more
europepmc +1 more source
A beneficial fungal root endophyte triggers systemic RNA silencing and DNA methylation of a host reporter gene. [PDF]
Dalakouras A +8 more
europepmc +1 more source

