Results 211 to 220 of about 7,567,038 (395)

Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. [PDF]

open access: yesCancers (Basel), 2022
Li Y   +11 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Three isoforms of <i>Brugia malayi</i> <i>daf-16</i> activate a reporter gene in cultured HepG2 cells. [PDF]

open access: yesMicroPubl Biol
Zehr CE   +4 more
europepmc   +1 more source

MOESM6 of Effect of secretory pathway gene overexpression on secretion of a fluorescent reporter protein in Aspergillus nidulans

open access: gold, 2016
Martin Schalén   +3 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

A beneficial fungal root endophyte triggers systemic RNA silencing and DNA methylation of a host reporter gene. [PDF]

open access: yesRNA Biol, 2023
Dalakouras A   +8 more
europepmc   +1 more source

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