Results 241 to 250 of about 550,187 (318)

Generation and identification of a thyroid cancer cell line with stable expression of CCDC67 and luciferase reporter genes. [PDF]

Oncol Lett, 2019
Zhang L, Wang L, Lei M, Ma R, Yu F, Liu C, Yin D.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Hypoxia-Induced Reporter Genes with Different Half-Lives. [PDF]

Methods Mol Biol, 2018
Krishnamachary B, Danhier P, Kakkad S, Bharti SK, Bhujwalla ZM.   +4 more
europepmc   +1 more source

Host-Cell Reactivation of a UV-Damaged Reporter Gene in Unirradiated and Pre-UV-Irradiated Rodent Cells

, 2003
Lili Liu
openalex   +1 more source

Reviewer #1 (Public review): Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution

Alastair J Tulloch, Ryan N. Delgado, Rinaldo Catta-Preta, Constance L Cepko   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes

, 2020
Chiem K, Vasquez DM, Park J, Platt RN, Anderson T, Walter MR, Kobie JJ, Ye C, Martinez-Sobrido L.   +8 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Second generation of pepino mosaic virus vectors: improved stability in tomato and a wide range of reporter genes. [PDF]

Plant Methods, 2019
Ruiz-Ramón F, Sempere RN, Méndez-López E, Sánchez-Pina MA, Aranda MA.   +4 more
europepmc   +1 more source

Foxc1 regulates Pecam-1 Expression in embryonic Endothelial Progenitor Cells [PDF]

, 2008
Lamparter, Mathias
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