Results 141 to 150 of about 21,585,462 (349)

Transparent reporting items for simulation studies evaluating statistical methods: Foundations for reproducibility and reliability

Methods in Ecology and Evolution
Simulation studies are essential tools to assess statistical methods. Functioning as controlled experiments, simulations generate data from known underlying processes.
Coralie Williams, Yefeng Yang, Malgorzata Lagisz, Kyle Morrison, Lorenzo Ricolfi, David I. Warton, Shinichi Nakagawa   +6 more
doaj   +1 more source

Use and reporting of systematic review methodology in EFSA scientific opinions on animal health and welfare

Frontiers in Veterinary Science
IntroductionDespite the growing use of systematic reviews of animal studies, it remains unclear how often systematic review methodology – such as detailed search strategies, critical appraisal, and protocol registration – is applied in regulatory ...
Johann Liesner, Johann Liesner, Benjamin V. Ineichen, Benjamin V. Ineichen, Marianna Rosso   +4 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

“How are you feeling?” Assessing reporting bias in a subjective measure of health by quantile regression [PDF]

In this paper we investigate reporting heterogeneity in the Visual Analogue Scale (VAS) when it is used to measure current health status in cardiovascular patients. We provide a new framework to identify reporting heterogeneity using quantile regressions.
Lunde, Lene, Løken, Katrine Vellesen
core  

Pengaruh Pemahaman Akuntansi, Sistem Akuntansi Keuangan Pemerintah Daerah dan Teknologi Informasi terhadap Kualitas Laporan Keuangan Pemerintah Daerah (Studi pada Skpd Kabupaten Indragiri Hilir) [PDF]

, 2016
This study aims to determine the effect of understanding of accounting to the quality of financial reporting area, the effect of the accounting system of local government finance to the quality of financial reporting area and the influence of information
Aniftahudin, A. (Aniftahudin), Hanif, R. A. (Rheny), Kamaliah, K. (Kamaliah)   +2 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Effect of COVID-19 on Public and Private Sector Earnings Management: Evidence from Korea

International Journal of Financial Studies
This study investigated how the COVID-19 pandemic impacted earnings management practices within both public and private firms in Korea. Amid active government efforts and policies to overcome the pandemic crisis, we anticipate that the earnings ...
Woo-sahng Kim, Bo-young Moon, Dong-goo Jung   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source