Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Operation and experiences of the second generation of the Schengen evaluation system
Belügyi SzemleAim: This study aims to explore and summarise nearly a decade of the operations of the second-generation Schengen evaluations, along with the direct experiences related to its implementation.
Lénárd Zsákai
doaj +1 more source
Diasporic Cinema: The Representation of Immigrants in Post-2000 German Films
, 2023 Tuğba KOÇAK
openalex +1 more source
Diffusion-Based Representation Learning [PDF]
, 2021 Korbinian Abstreiter +4 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
ARCHive-SRThe study we present is related to a scan-to-BIM process carried out on the Romanesque-Byzantine church of San Giovannello, located in the historic center of Gerace (Reggio Calabria, Italy). The work is part of a broader research project, called GENESIS
Marinella Arena +3 more
doaj +1 more source
Participatory Design for Cultural Representation: A Cultural Transparency Perspective [PDF]
, 2013 Amalia Sabiescu, Nemanja Memarović
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Representation Matters: An Unexpected Property of Polynomial Rings and its Consequences for Formalizing Abstract Field Theory [PDF]
, 2018 Christoph Schwarzweller
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source