Results 71 to 80 of about 1,442,725 (246)
From Fragmented Repertoires to a Property Graph: A Queryable Atlas of Byzantine Geometric Mosaic Bands for Architectural Heritage [PDF]
Research often focuses on architecture as a whole, seeking to explore its various scales as thoroughly as possible. However, some aspects, such as decorative friezes, play a decisive role not only in terms of decoration but also in understanding ...
G. Flenghi +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Manipulating Representations [PDF]
The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species), and puts forward the idea of a progressive ontological development of consciousness from a state of 'childhood' awareness, in order to explain that humans are not only able to manipulate objects, but also ...
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
ACHIEVEMENTS OF THE FIRM EGES IN PRODUCTION OF FURNACE SYSTEMS
The modern developments of the firm EGES of induction mid-frequency furnaces are ...
F. Koch, A. M. Shtypa
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Multi-Layered 3D Survey Process to Represent Visible and Invisible Data [PDF]
Over the last 25 years, active and passive 3D survey techniques applied in the Cultural Heritage domain have achieved a high degree of reliability. The degree of maturity in the integrated use of these methodologies is well exemplified by their broad ...
M. Russo, V. Cera, M. Casciola, M. Porcu
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A City with a Sense. Back to Kevin Lynch’s The Image of the City
At the beginning of the 1960s three of the most influential books on the topic of the analysis and design of cities were published. These were The Image of the City by Kevin Lynch [Lynch 1960], Townscape by Gordon Cullen [Cullen 1961], and The Death and
Carlos Montes Serrano
doaj +1 more source

